Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Nutrition Support in Cardiac Surgery Patients—A Narrative Review

Version 1 : Received: 6 April 2018 / Approved: 8 April 2018 / Online: 8 April 2018 (10:24:31 CEST)

A peer-reviewed article of this Preprint also exists.

Hill, A.; Nesterova, E.; Lomivorotov, V.; Efremov, S.; Goetzenich, A.; Benstoem, C.; Zamyatin, M.; Chourdakis, M.; Heyland, D.; Stoppe, C. Current Evidence about Nutrition Support in Cardiac Surgery Patients—What Do We Know? Nutrients 2018, 10, 597. Hill, A.; Nesterova, E.; Lomivorotov, V.; Efremov, S.; Goetzenich, A.; Benstoem, C.; Zamyatin, M.; Chourdakis, M.; Heyland, D.; Stoppe, C. Current Evidence about Nutrition Support in Cardiac Surgery Patients—What Do We Know? Nutrients 2018, 10, 597.

Abstract

Nutrition support is increasingly recognized as a clinically relevant aspect of the intensive care treatment of cardiac surgery patients. However, evidence from adequate large-scale studies evaluating its clinical significance for patients’ mid- to long-term outcome remains sparse. Considering nutrition support as a key component in the perioperative treatment of these critically ill patients, led us to review and discuss our understanding of the metabolic response to the inflammatory burst induced by cardiac surgery. In addition, we discuss how to identify patients who may benefit from nutrition therapy, when to start nutritional interventions, present evidence about the use of enteral and parenteral nutrition and the potential role of pharmaconutrition in cardiac surgery patients. Although the clinical setting of cardiac surgery provides advantages due to its scheduled insult and predictable inflammatory response, researchers and clinicians face lack of evidence and several limitations in the clinical routine, which are critically considered and discussed in this paper.

Keywords

cardiac surgery; cardiopulmonary bypass; systemic inflammatory response; nutrition risk stratification; underfeeding; postoperative nutritional management; supplemental parenteral nutrition; enteral nutrition; pharmaconutrition

Subject

Medicine and Pharmacology, Dietetics and Nutrition

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