Preprint Review Version 1 This version is not peer-reviewed

Clinical Applications of Low-Level Laser Therapy in Reproductive Medicine; A Literature Review

Version 1 : Received: 4 April 2018 / Approved: 8 April 2018 / Online: 8 April 2018 (08:35:22 CEST)

How to cite: Borhani, S.; Yazdi, R.S. Clinical Applications of Low-Level Laser Therapy in Reproductive Medicine; A Literature Review. Preprints 2018, 2018040086 (doi: 10.20944/preprints201804.0086.v1). Borhani, S.; Yazdi, R.S. Clinical Applications of Low-Level Laser Therapy in Reproductive Medicine; A Literature Review. Preprints 2018, 2018040086 (doi: 10.20944/preprints201804.0086.v1).

Abstract

Infertility affects approximately 15% of couples worldwide, an estimated 30% of which is related to male factor infertility. Application of low level laser therapy (LLLT) to improve fertility status is a rapidly growing discipline in medicine. Laser therapy triggers a variety of biological processes through interaction with primary cellular photoacceptors. The present review aims at evaluating the literature available in the MEDLINE/ PubMed on cellular and molecular mechanisms of photobiomodulation in the domains of reproductive and veterinary medicine. We primarily focused on the clinical application of laser treatment on seminal quality, in particular its role in promoting spermatozoa motility, as well as the role of phototherapy in modulating assisted reproduction (ART). Additionally, we investigated the strength of evidence in support of the positive impact of photobiomodulation on facilitating ART.

Subject Areas

low-level laser therapy (LLLT); photobiomodulation; male infertility; sperm motility; assisted reproductive technology (ART)

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