Preprint Article Version 1 This version is not peer-reviewed

Progress on the Use of Commercial Digital Optical Disc Units for Low-Power Laser Micromachining in Biomedical Applications

Version 1 : Received: 23 March 2018 / Approved: 23 March 2018 / Online: 23 March 2018 (08:00:52 CET)

A peer-reviewed article of this Preprint also exists.

Cruz-Ramírez, A.; Sánchez-Olvera, R.; Zamarrón-Hernández, D.; Hautefeuille, M.; Cabriales, L.; Jiménez-Díaz, E.; Díaz-Bello, B.; López-Aparicio, J.; Pérez-Calixto, D.; Cano-Jorge, M.; Vázquez-Victorio, G. Progress on the Use of Commercial Digital Optical Disc Units for Low-Power Laser Micromachining in Biomedical Applications. Micromachines 2018, 9, 187. Cruz-Ramírez, A.; Sánchez-Olvera, R.; Zamarrón-Hernández, D.; Hautefeuille, M.; Cabriales, L.; Jiménez-Díaz, E.; Díaz-Bello, B.; López-Aparicio, J.; Pérez-Calixto, D.; Cano-Jorge, M.; Vázquez-Victorio, G. Progress on the Use of Commercial Digital Optical Disc Units for Low-Power Laser Micromachining in Biomedical Applications. Micromachines 2018, 9, 187.

Journal reference: Micromachines 2018, 9, 187
DOI: 10.3390/mi9040187

Abstract

The development of organ-on-chip and biological scaffolds is currently requiring simpler methods to microstructure biocompatible materials in three dimensions, fabricate structural and functional elements in biomaterials or modify the physicochemical properties of desired substrates. Aiming at addressing this need, a low-power CD-DVD-Blu-ray laser pickup head was mounted on a programmable three-axis micro-displacement system in order to modify the surface of polymeric materials in a local fashion. Thanks to a specially-designed method using a strongly absorbing additive coating the materials of interest, it has been possible to establish and precisely control processes useful in microtechnology for biomedical applications. The system was upgraded with blu-ray laser for additive manufacturing and ablation on a single platform. In this work, we present the application of these fabrication techniques to the development of biomimetic cellular culture platforms thanks to the simple integration of several features typically achieved with traditional, less cost-effective microtechnology methods in one step or through replica-molding. Our straightforward approach indeed enables great control of local laser microablation or polymerization for true on-demand biomimetic micropatterned designs in transparent polymers and hydrogels and is allowing integration of microfluidics, microelectronics, surface microstructuring and transfer of superficial protein micropatterns on a variety of biocompatible materials.

Subject Areas

laser micromachining; scaffold; biomimetics; microadditive manufacturing; microsubtractive manufacturing

Readers' Comments and Ratings (0)

Leave a public comment
Send a private comment to the author(s)
Rate this article
Views 0
Downloads 0
Comments 0
Metrics 0
Leave a public comment

×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.