New Cassane Diterpenoids from Caesalpinia sappan and Their Antiplasmodial Activity

Nai-Liang Zhu; Zhong-Hao Sun; Mei-Geng Hu; Tong-Yu Wu; Jing-Quan Yuan; Hai-Feng Wu; Yu Tian; Peng-Fei Li; Jun-Shan Yang; Guo-Xu Ma; Xu-Dong Xu

doi:10.20944/preprints201710.0088.v1

A peer-reviewed article of this Preprint also exists.

Zhu, N.-L.; Sun, Z.-H.; Hu, M.-G.; Wu, T.-Y.; Yuan, J.-Q.; Wu, H.-F.; Tian, Y.; Li, P.-F.; Yang, J.-S.; Ma, G.-X.; Xu, X.-D. New Cassane Diterpenoids from Caesalpinia sappan and their Antiplasmodial Activity. Molecules 2017, 22, 1751. Zhu, N.-L.; Sun, Z.-H.; Hu, M.-G.; Wu, T.-Y.; Yuan, J.-Q.; Wu, H.-F.; Tian, Y.; Li, P.-F.; Yang, J.-S.; Ma, G.-X.; Xu, X.-D. New Cassane Diterpenoids from Caesalpinia sappan and their Antiplasmodial Activity. Molecules 2017, 22, 1751.

Abstract

One new cassane diterpene possessing an unusual N bridge between C-19 and C-20 named caesalsappanin R (1), as well as another new diterpene caesalsappanin S (2), were isolated from the seeds of Caesalpinia sappan with methanol extract. Their structures were determined by spectroscopic analysis and examined alongside existing data from prior studies. Their biological activities were profiled by their antiplasmodial activity.

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New Cassane Diterpenoids from Caesalpinia sappan and Their Antiplasmodial Activity

Abstract

Keywords

Subject

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