Preprint Review Version 1 This version is not peer-reviewed

Non-Coding RNAs Mediate Chemotherapy Resistance in Ovarian Cancer

Version 1 : Received: 3 October 2017 / Approved: 4 October 2017 / Online: 4 October 2017 (11:59:09 CEST)

How to cite: Shao, Y.; Li, H.; Du, R.; Meng, J.; Yang, G. Non-Coding RNAs Mediate Chemotherapy Resistance in Ovarian Cancer. Preprints 2017, 2017100021 (doi: 10.20944/preprints201710.0021.v1). Shao, Y.; Li, H.; Du, R.; Meng, J.; Yang, G. Non-Coding RNAs Mediate Chemotherapy Resistance in Ovarian Cancer. Preprints 2017, 2017100021 (doi: 10.20944/preprints201710.0021.v1).

Abstract

With the advancement of next generation sequencing in past several years, a rising number of non-coding RNAs have been found as new actors to regulate gene expression. Non-coding RNAs not only play important roles in carcinogenesis, but also affect the clinical treatment strategies. They have been proved to be deeply correlated with chemoresistance in several cancers. Ovarian cancer is the leading cause of death in gynecological malignancy, with low 5-year survival rate. Most patients are identified when they have late-stage disease. This review mainly makes a compilation of the most relevant research literature in this field with the purpose of shedding light on the relation between ncRNAs and chemoresistance in ovarian cancer.

Subject Areas

ncRNAs; ovarian cancer; chemoresistance

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