Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Principles of Dynamic Network Reconfiguration across Diverse Brain States

Version 1 : Received: 9 July 2017 / Approved: 10 July 2017 / Online: 10 July 2017 (05:48:41 CEST)

A peer-reviewed article of this Preprint also exists.


Recent methodological advances have enabled researchers to track the network structure of the human brain over time. Together, these studies provide novel insights into effective brain function, highlighting the importance of the systems-level perspective in understanding the manner in which the human brain organizes its activity to facilitate behavior. Here, we review a range of recent fMRI and electrophysiological studies that have mapped the relationship between inter-regional communication and network structure across a diverse range of brain states. In doing so, we identify both behavioral and biological axes that may underlie the tendency for network reconfiguration. We conclude our review by providing suggestions for future research endeavors that may help to refine our understanding of the functioning of the human brain.


network; topology; integration; segregation; fMRI


Medicine and Pharmacology, Neuroscience and Neurology

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