Preprint Communication Version 1 This version is not peer-reviewed

Microindolinone A, a Novel 4,5,6,7-Tetrahydroindole, from the Deep-Sea-Derived Actinomycete Microbacterium sp. MCCC 1A11207

Version 1 : Received: 14 June 2017 / Approved: 16 June 2017 / Online: 16 June 2017 (04:40:54 CEST)

A peer-reviewed article of this Preprint also exists.

Niu, S.; Zhou, T.-T.; Xie, C.-L.; Zhang, G.-Y.; Yang, X.-W. Microindolinone A, a Novel 4,5,6,7-Tetrahydroindole, from the Deep-Sea-Derived Actinomycete Microbacterium sp. MCCC 1A11207. Mar. Drugs 2017, 15, 230. Niu, S.; Zhou, T.-T.; Xie, C.-L.; Zhang, G.-Y.; Yang, X.-W. Microindolinone A, a Novel 4,5,6,7-Tetrahydroindole, from the Deep-Sea-Derived Actinomycete Microbacterium sp. MCCC 1A11207. Mar. Drugs 2017, 15, 230.

Journal reference: Mar. Drugs 2017, 15, 230
DOI: 10.3390/md15070230

Abstract

A novel indole, microindolinone A (1), was isolated from a deep-sea-derived actinomycete Microbacterium sp. MCCC 1A11207, together with 18 known compounds (219). By detailed analysis of the 1H, 13C, HSQC, COSY, HMBC, HRESIMS, and CD data, the absolute configuration of 1 was elucidated as 5R-hydroxy-4,5,6,7-tetrahydroindole-4-one. Noteworthily, 1 is the second example of a saturated indole isolated from nature.

Subject Areas

deep-sea; actinomycete; Microbacterium sp.; indole

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