Preprint Short Note Version 1 Preserved in Portico This version is not peer-reviewed

Prevalence of Human Norovirus by Genotype in Contaminated Groundwater in Korea Over the Last Decade (2007-2016)

Version 1 : Received: 5 June 2017 / Approved: 5 June 2017 / Online: 5 June 2017 (05:43:56 CEST)

How to cite: Lee, S.; Park, S.; Kim, J.; Lee, W.; Chung, H. Prevalence of Human Norovirus by Genotype in Contaminated Groundwater in Korea Over the Last Decade (2007-2016). Preprints 2017, 2017060027. https://doi.org/10.20944/preprints201706.0027.v1 Lee, S.; Park, S.; Kim, J.; Lee, W.; Chung, H. Prevalence of Human Norovirus by Genotype in Contaminated Groundwater in Korea Over the Last Decade (2007-2016). Preprints 2017, 2017060027. https://doi.org/10.20944/preprints201706.0027.v1

Abstract

This study investigated the presence of human Norovirus (HuNoV) by genotype in 1,486 groundwater samples, collected from 843 groundwater wells suspected of contamination during 2007-2016, in Republic of Korea. We identified and genotyped 186 HuNoV sequences in 178 HuNoV-positive samples using the RIVM-NoroNet norovirus genotyping tool (NGT) and phylogenetic tree analysis based on RIVM-NoroNet reference sequences. HuNoV GII was more prevalent than GI. The major genotypes detected were HuNoV GII.4 (43.0%), GII.22 (15.6%), GI.5 (10.2%) and GI.1 (8.6%); 14 genotypes accounted for < 5.0%. Increasing HuNoV GII.17 has displayed a worldwide trend, including in Europe and Asia since 2010, and it was the dominant HuNoV genotype during 2013-2014 in Korea. However, HuNoV GII.4 was the major genotype detected in groundwater in Korea in 2015-2016, and it is becoming increasingly prevalent similar to HuNoV GII.17.

Keywords

genotype; groundwater; human norovirus; HuNoV; HuNoV genotype

Subject

Biology and Life Sciences, Virology

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Comment 1
Received: 9 June 2017
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The commenter has declared there is no conflict of interests.
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