Preserved in Portico This version is not peer-reviewed
Influenza Virus Infection, Interferon Response, Viral Counter-Response, and Apoptosis
: Received: 30 May 2017 / Approved: 30 May 2017 / Online: 30 May 2017 (07:13:09 CEST)
: Received: 12 August 2017 / Approved: 14 August 2017 / Online: 14 August 2017 (04:41:22 CEST)
A peer-reviewed article of this Preprint also exists.
Journal reference: Viruses 2017, 9, 223
Human influenza A viruses (IAVs) cause global pandemics and epidemics, which remain serious threats to public health because of the shortage of effective means of control. To combat the surge of viral outbreaks, new treatments are urgently needed. Developing new virus control modalities requires better understanding of virus-host interactions. Here we describe how IAV infection triggers cellular apoptosis, and how this process can be exploited towards development of new therapeutics, which might be more effective than the currently available anti-influenza drugs.
influenza virus; apoptosis; antiviral agent; innate immunity; host response
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