Preprint Review Version 1 This version is not peer-reviewed

Oral Mucositis: Melatonin Gel an Effective New Treatment

Version 1 : Received: 8 March 2017 / Approved: 9 March 2017 / Online: 9 March 2017 (04:46:30 CET)

A peer-reviewed article of this Preprint also exists.

Abdel Moneim, A.E.; Guerra-Librero, A.; Florido, J.; Shen, Y.-Q.; Fernández-Gil, B.; Acuña-Castroviejo, D.; Escames, G. Oral Mucositis: Melatonin Gel an Effective New Treatment. Int. J. Mol. Sci. 2017, 18, 1003. Abdel Moneim, A.E.; Guerra-Librero, A.; Florido, J.; Shen, Y.-Q.; Fernández-Gil, B.; Acuña-Castroviejo, D.; Escames, G. Oral Mucositis: Melatonin Gel an Effective New Treatment. Int. J. Mol. Sci. 2017, 18, 1003.

Journal reference: Int. J. Mol. Sci. 2017, 18, 1003
DOI: 10.3390/ijms18051003

Abstract

The current treatment for cervico-facial cancer involves radio and/or chemotherapy. Unfortunately, cancer therapies can lead to local and systemic complications such as mucositis, which is the most common dose-dependent complication in the oral cavity and gastrointestinal tract. Mucositis can cause a considerably reduced quality of life in cancer patients already suffering from physical and psychological exhaustion. However, melatonin, whose role in the treatment of mucositis has recently been investigated, offers an effective alternative therapy in the prevention and/or management of radio and/or chemotherapy-induced mucositis. This review focuses on the pathobiology and management of mucositis in order to improve the quality of cancer patients’ lives.

Subject Areas

mucositis; radiotherapy; chemotherapy; pathophysiology; management; melatonin

Readers' Comments and Ratings (0)

Leave a public comment
Send a private comment to the author(s)
Rate this article
Views 0
Downloads 0
Comments 0
Metrics 0
Leave a public comment

×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.