Preprint Article Version 1 NOT YET PEER-REVIEWED

4-Hydroxy-2-nonenal Statues in Hypertension Patients

Version 1 : Received: 5 March 2017 / Approved: 7 March 2017 / Online: 7 March 2017 (07:00:16 CET)

How to cite: Jawad, A.; Ibrahim, A.; Hammed, A.; Al-Qaisi, Z.; Redwan, A.; Yousif, E. 4-Hydroxy-2-nonenal Statues in Hypertension Patients. Preprints 2017, 2017030037 (doi: 10.20944/preprints201703.0037.v1). Jawad, A.; Ibrahim, A.; Hammed, A.; Al-Qaisi, Z.; Redwan, A.; Yousif, E. 4-Hydroxy-2-nonenal Statues in Hypertension Patients. Preprints 2017, 2017030037 (doi: 10.20944/preprints201703.0037.v1).

Abstract

The oxidative stress is one of the main cause for cardiovascular diseases  (like Hypertension) also one of the results of these diseases.  This study involved 56 subjects matched ages  and sex divided into two groups; 28 hypertensive subject and 28 healthy subject as control group. The following analysis was done: 4-Hydroxy-2-nonenal(4HNE) and albumin. The results show that there is a significant increase in (4HNE) between patients group and control group. The increase in 4HNE which is a product of lipid peroxidation  is attributed to destruction in body cell caused by due to the increase in stress events. It has been concluded that is important nappy on ideal weight, because obesity considered main factors for heart disease and hardening of the arteries. The aim of this study was to investigate the relationship between of some oxidative stress markers and cardiovascular diseases.

Subject Areas

hypertension; 4-hydroxy-2-nonenal (4HNE); reactive oxygen species(ROS)

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