Version 1
: Received: 22 December 2016 / Approved: 23 December 2016 / Online: 23 December 2016 (13:37:44 CET)
How to cite:
Baldassano, S.; Buscemi, S.; Aiello, A.; Accardi, G.; Caruso, C.; Vasto, S. β-Glucans and Post Prandial Satiety: The Role of Intestinal Hormones in Healthy Volunteers. Preprints2016, 2016120120. https://doi.org/10.20944/preprints201612.0120.v1
Baldassano, S.; Buscemi, S.; Aiello, A.; Accardi, G.; Caruso, C.; Vasto, S. β-Glucans and Post Prandial Satiety: The Role of Intestinal Hormones in Healthy Volunteers. Preprints 2016, 2016120120. https://doi.org/10.20944/preprints201612.0120.v1
Baldassano, S.; Buscemi, S.; Aiello, A.; Accardi, G.; Caruso, C.; Vasto, S. β-Glucans and Post Prandial Satiety: The Role of Intestinal Hormones in Healthy Volunteers. Preprints2016, 2016120120. https://doi.org/10.20944/preprints201612.0120.v1
APA Style
Baldassano, S., Buscemi, S., Aiello, A., Accardi, G., Caruso, C., & Vasto, S. (2016). β-Glucans and Post Prandial Satiety: The Role of Intestinal Hormones in Healthy Volunteers. Preprints. https://doi.org/10.20944/preprints201612.0120.v1
Chicago/Turabian Style
Baldassano, S., Calogero Caruso and Sonya Vasto. 2016 "β-Glucans and Post Prandial Satiety: The Role of Intestinal Hormones in Healthy Volunteers" Preprints. https://doi.org/10.20944/preprints201612.0120.v1
Abstract
Recent interest in intestinal hormones has risen with the idea that they modulate glucose tolerance and food intake through a variety of mechanisms, and such hormones like peptide YY (PYY), ghrelin, glucagon-like peptide (GLP)-1 and 2, and cholecystokinin (CKK) are therefore excellent therapeutic candidates for the treatment of diabetes and obesity. Furthermore, in the recent years, multiple studies suggest that the microbiota is critically important for normal host functions, while impaired host microbiota interactions contribute to the pathogenesis of numerous common metabolic disorders. In this study, we considered the nutraceutical effects of β-glucans added to pasta at the concentration of 6g\100g. Ten participants have been recruited and hematochemical analyses and intestinal hormones tests have been performed before and after 30 days of pasta intake. Stool specimens have been studied for Lactobacillus Fermentum,Lactobacillus acidophilus, Lactobacillus salivarius, Bifidobacterium longum, and Enterococcus faecium presence before and after 30 days of nutritional intervention. After 30 days of regular intake of pasta enriched by β-glucans results have been evaluated. In conclusion, pasta prepared from barley flour enriched with β-glucans at 6% exhibit promising responses on glucose metabolism, on intestinal hormones responses and on microbiota modification.
Medicine and Pharmacology, Gastroenterology and Hepatology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.