Article
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Tissue-Like Phantoms as a Platform for Inserted Fluorescence Nano-Probes
Version 1
: Received: 26 October 2016 / Approved: 27 October 2016 / Online: 27 October 2016 (11:52:21 CEST)
A peer-reviewed article of this Preprint also exists.
Nayhoz, T.; Barnoy, E.A.; Fixler, D. Tissue-Like Phantoms as a Platform for Inserted Fluorescence Nano-Probes. Materials 2016, 9, 926. Nayhoz, T.; Barnoy, E.A.; Fixler, D. Tissue-Like Phantoms as a Platform for Inserted Fluorescence Nano-Probes. Materials 2016, 9, 926.
Abstract
Tissue-like phantoms are widely used as a model for mimicking the optical properties of live tissue. This paper presents the results of a diffusion reflection method as well as fluorescence lifetime imaging microscopy measurements of fluorescein-conjugated gold nanorods in solution as well as inserted in solid tissue-imitating phantoms. A lack of consistency between the fluorescence lifetime results of the solutions and the phantoms raises a question about the ability of tissue-like phantoms to maintain the optical properties of inserted contrast agents.
Keywords
tissue-like phantoms; dual-modal imaging; fluorescence lifetime (FLT); FLT imaging (FLIM); diffusion reflection
Subject
Physical Sciences, Optics and Photonics
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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