Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

A Review of PMMA Bone Cement and Intra-Cardiac Embolism

Puneeth Shridhar
ORCID logo ,
Yanfei Chen
ORCID logo ,
Ramzi Khalil
,
Anton Plakseyhuk
,
Sung Kwon Cho
,
Bryan Tillman
,
Prashant N. Kumta
,
Youngjae Chun
* ORCID logo
Version 1 : Received: 23 September 2016 / Approved: 26 September 2016 / Online: 26 September 2016 (10:34:26 CEST)

A peer-reviewed article of this Preprint also exists.

Shridhar, P.; Chen, Y.; Khalil, R.; Plakseychuk, A.; Cho, S.K.; Tillman, B.; Kumta, P.N.; Chun, Y. A Review of PMMA Bone Cement and Intra‐Cardiac Embolism. Materials 2016, 9, 821. Shridhar, P.; Chen, Y.; Khalil, R.; Plakseychuk, A.; Cho, S.K.; Tillman, B.; Kumta, P.N.; Chun, Y. A Review of PMMA Bone Cement and Intra‐Cardiac Embolism. Materials 2016, 9, 821.

DOI: 10.3390/ma9100821

Abstract

Percutaneous vertebroplasty procedure is of major importance, given the significant increasing aging population and higher number of orthopedic procedures related to vertebral compression fractures. Vertebroplasty is a complex technique involving injection of polymethylmethacrylate (PMMA) into the compressed vertebral body for mechanical stabilization of the fracture. Our understanding and ability to modify these mechanisms through alterations in cement material is rapidly evolving. However, the rate of cardiac complications secondary to PMMA injection and subsequent cement leakage has increased with time. The following review considers the main features of PMMA bone cement on the heart, and the extent of influence of materials on cardiac embolism. Clinically, cement leakage results in life-threatening cardiac injury. The convolution of this outcome through an appropriate balance of complex material properties is highlighted via clinical case report.

Keywords

PMMA; bone cement; cardiac embolism; cement leakage; viscosity

Subject

MATERIALS SCIENCE, Biomaterials

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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