Version 1
: Received: 19 August 2016 / Approved: 23 August 2016 / Online: 23 August 2016 (11:25:42 CEST)
How to cite:
Nain, Z.; Islam, M.A.; Chowdhury, S.H.; Afroza, S. Current Understanding on Tail Regeneration in Green Anoles (Anolis carolinensis). Preprints2016, 2016080195. https://doi.org/10.20944/preprints201608.0195.v1
Nain, Z.; Islam, M.A.; Chowdhury, S.H.; Afroza, S. Current Understanding on Tail Regeneration in Green Anoles (Anolis carolinensis). Preprints 2016, 2016080195. https://doi.org/10.20944/preprints201608.0195.v1
Nain, Z.; Islam, M.A.; Chowdhury, S.H.; Afroza, S. Current Understanding on Tail Regeneration in Green Anoles (Anolis carolinensis). Preprints2016, 2016080195. https://doi.org/10.20944/preprints201608.0195.v1
APA Style
Nain, Z., Islam, M.A., Chowdhury, S.H., & Afroza, S. (2016). Current Understanding on Tail Regeneration in Green Anoles (Anolis carolinensis). Preprints. https://doi.org/10.20944/preprints201608.0195.v1
Chicago/Turabian Style
Nain, Z., Sadrul Hasan Chowdhury and Sadia Afroza. 2016 "Current Understanding on Tail Regeneration in Green Anoles (Anolis carolinensis)" Preprints. https://doi.org/10.20944/preprints201608.0195.v1
Abstract
Regeneration of lost tail is of great importance to lizards. Anolis carolinensis, a green lizard, is capable of regenerating its tail efficiently after autotomy. Hence, it is considered as a model organism in regeneration study. A. carolinensis shed its tail in order to distract the predator’s attention and thus makes a way to escape. Restoring of the amputated tail takes several days and the mechanism is currently clearly understood. Although save its life, tail regeneration is associated with the impairment of several vital functions in Anoles. In addition, various differences have been observed between original and regenerated tail in terms of mechanism and structure. To date, very little work has been conducted on tail autotomy and regeneration at molecular and genetic level. The genes responsible for regeneration in anoles are identified recently. These genes are evolutionarily conserved through all tetrapod vertebrates. They are, however, in a state of ‘switched-off’ in other vertebrates including humans. Consequently, a throughout study of these so called ‘switched-off’ genes may provide a way of restoring lost organs in human, and thus could revolutionize the modern medical science.
Keywords
green anole; tail autotomy; regeneration; microRNAs; Anolis carolinensis
Subject
Biology and Life Sciences, Cell and Developmental Biology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
