Global warming is increasing the frequency and intensity of compound drought-heat events (CDHEs), potentially leading to larger and more extreme fire seasons in mesic forests. Wildfire activity in subtropical China, under the influence of monsoonal rainfall, was historically limited to dry winters and rare in rainy summers. Here we seek to test that this area is on the brink of a major change in its fire regime characterized by larger fire seasons, extending into the summer, leading to increases in burned area. We analyze fire activity in Chongqing Municipality (46,890 km2), an important area in subtropical China hosting the Three Gorges Reservoir Area. We observed significant increases in summer forest fires under anomalous dry-hot summer conditions, where total burned area was 3-6 higher than the historical annual mean (largely confined to the winter season). Vapor pressure deficit, an indicator of hot and dry conditions, was a strong predictor of fire activity, with major wildfires occurring on days where VPD was higher than 3.5kPa. Results indicate that major wildfire activity may occur in the area as a result of climate change, unless strong fire prevention policies are implemented.