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Preprint ARTICLE | doi:10.20944/preprints202302.0317.v1

SBOannotator: a Python Tool for the Automated Assignment of Systems Biology Ontology Terms

Nantia Leonidou, Elisabeth Fritze, Alina Renz, Andreas Dräger

Subject: Computer Science And Mathematics, Computer Science Keywords: SBOannotator; ontologies; SBO terms; Python; software; automated assignment; computational modeling; systems biology

Online: 20 February 2023 (03:57:56 CET)

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Preprint ARTICLE | doi:10.20944/preprints202203.0290.v3

New Workflow Predicts Drug Targets Against SARS-CoV-2 via Metabolic Changes in Infected Cells

Nantia Leonidou, Alina Renz, Reihaneh Mostolizadeh, Andreas Dräger

Subject: Biology And Life Sciences, Biology And Biotechnology Keywords: host-virus interactions; tissue-specific model; COVID-19; SARS-CoV-2; antiviral targets; flux balance analysis; flux variability analysis; reaction knockout; host-derived enforcement; metabolic modeling; virus mutations; software engineering; Python

Online: 17 January 2023 (01:50:23 CET)

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Preprint ARTICLE | doi:10.20944/preprints202210.0223.v3

Metabolic Modeling Elucidates Phenformin and Atpenin A5 as Broad-Spectrum Antiviral Drugs

Alina Renz, Mirjam Hohner, Maximilian Breitenbach, Jonathan Josephs-Spaulding, Johanna Dürrwald, Lena Best, Victoria Dulière, Chloé Mialon, Stefanie M. Bader, Raphaël Jami, Georgios Marinos, Nantia Leonidou, Filipe Cabreiro, Marc Pellegrini, Marcel Doerflinger, Manuel Rosa-Calatrava, Andrés Pizzorno, Andreas Dräger, Michael Schindler, Christoph Kaleta

Subject: Biology And Life Sciences, Virology Keywords: Drug discovery; Systems biology; SARS-CoV-2; Dengue; Influenza A; RSV; cell viability analysis; antivirals; in vitro validation; in vivo validation

Online: 22 March 2024 (16:46:59 CET)

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