REVIEW | doi:10.20944/preprints201608.0036.v1
Subject: Chemistry And Materials Science, Organic Chemistry Keywords: hydrogels; tissue engineering; bioconjugation
Online: 4 August 2016 (11:00:19 CEST)
Disease, trauma, and aging account for a significant number of clinical disorders. Regenerative medicine is emerging as a very promising therapeutic option. The design and development of new cell-customized biomaterials able to mimic ECM functionalities represent one of the major strategy to control the cell fate and stimulate tissue regeneration. Recently, hydrogels have received a considerable interest for their use in the modulation and control of cell fate during regeneration processes. Several synthetic bioresponsive hydrogels are being developed in order to facilitate cell-matrix and cell-cell interactions. In this review new strategies and future perspectives of such synthetic cell microenvironment will be highlighted.