Submitted:
03 August 2026
Posted:
04 August 2026
You are already at the latest version
Abstract
Keywords:
1. Introduction
Specific Objectives
- To explore the social, contextual, and individual factors associated with the initiation of psychoactive substance use, with an emphasis on the specific vulnerabilities of early onset and exposure to criminogenic environments.
- To examine participants’ subjective experiences of the effects of substance use, dependence, and withdrawal, including the impact on psychological and behavioral functioning.
- To analyze the cognitive and social mechanisms sustaining addictive behavior, including patterns of responsibility attribution and the relationship between substance use and criminal behavior.
- To investigate the role of the family as a protective factor and/or risk factor along the trajectory of substance use, within the theoretical framework of the recovery capital concept.
- To identify factors perceived as facilitators of or barriers to abstinence and recovery in the prison environment, including relevant institutional and relational resources.
- To examine participants’ perspectives on post-release social reintegration, including factors associated with the risk of recidivism and community reinsertion.
2. Materials and Methods
2.1. Study Design
2.2. Setting and Participants
2.3. Data Collection
2.4. Data Analysis
2.5. Trustworthiness and Rigor
2.6. Ethical Considerations
3. Results
3.1. Initiation Factors and Vulnerabilities Associated with the Onset of Illicit Drug Use
3.2. Clinical and Psychological Manifestations of Drug Use
3.3. The Experience of Dependence and Withdrawal
3.4. Cognitive and Social Mechanisms Sustaining Use
3.5. Family: Risk Factor, Protective Factor, and Source of Suffering
3.6. Recovery, Abstinence, and Identity Reconstruction
4. Discussion
4.1. The Experience of Use and Early Onset
4.2. Perceived Responsibility and Causal Attribution
4.3. Psychobehavioral Effects of Use, Withdrawal, and Dependence
4.4. The Family Between Risk Factor and Protective Factor, Economic Vulnerability
4.5. Abstinence and the Recovery Process
4.6. Attitude Toward Life, Normalization of Use, and Social Reintegration
5. Conclusions
Limitations
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Acknowledgments
Appendix A. Semi-Structured Interview Guide
Study Context
- What is your age?
- What is your place of residence prior to incarceration (urban/rural)?
- What is your marital status?
- Can you briefly describe your educational and occupational background?
- At what age did you first use drugs?
- What substances have you used?
- Can you describe the context in which you first used drugs (where were you, with whom, under what circumstances)?
- How long have you used drugs in total?
- How would you describe your experience while under the influence of drugs?
- How would you describe withdrawal symptoms and the experience of abstinence?
- On a scale from 1 to 10, who do you consider responsible for your drug use initiation (family, school, peers, community, society, yourself)?
- Can you explain why you assigned these levels of responsibility?
- What role did your family play in your upbringing and life development?
- How did you obtain financial resources to sustain drug use?
- Have you ever tried to stop using drugs? If yes, what motivated you?
- What helped you remain abstinent during those periods?
- How many times have you attempted to quit drug use?
- What were the main losses or negative consequences of drug use in your life?
- What do you consider the most effective way to overcome drug dependence?
- What advice would you give to someone trying to stop using drugs?
- What unmet needs have you experienced throughout your life?
- Do you experience feelings of guilt or remorse related to drug use? If yes, in what way?
- What is your biggest regret in life?
- What is your greatest source of joy or satisfaction?
- If you could change something in your life, what would it be?
- Please complete the sentence: “Life is worth living because…”
Ethical Framing Within Interview Process
- Participants were informed that participation was voluntary.
- They were assured that they could refuse to answer any question.
- Confidentiality and anonymity were guaranteed.
- No information provided was used for legal or institutional decision-making.
Notes on Use
References
- World Health Organization. Global Status Report on Alcohol and Health and Treatment of Substance Use Disorders; World Health Organization: Geneva, Switzerland, 2024. Available online: https://www.who.int/publications/i/item/9789240096745 (accessed on 10 March 2026).
- United Nations Office on Drugs and Crime (UNODC). World Drug Report 2024: Harms of World Drug Problem Continue to Mount Amid Expansions in Drug Use and Markets; UNODC: Vienna, Austria, 2024. Available online: https://www.unodc.org/unodc/press/releases/2024/June/unodc-world-drug-report-2024_-harms-of-world-drug-problem-continue-to-mount-amid-expansions-in-drug-use-and-markets.html (accessed on 10 February 2026).
- European Monitoring Centre for Drugs and Drug Addiction. European Drug Report 2024: Trends and Developments; EMCDDA: Lisbon, Portugal, 2024. Available online: https://www.emcdda.europa.eu (accessed on 3 January 2026).
- Brauer, M.; Roth, G.A.; Aravkin, A.Y.; Zheng, P.; Abate, K.H.; Abate, Y.H.; Abbafati, C.; Abbasgholizadeh, R.; Abbasi, M.A.; Abbasian, M.; et al. Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021: A systematic analysis for the Global Burden of Disease Study 2021. Lancet 2024, 403, 2162–2203, . [CrossRef]
- Kang, J.; Kim, H.J.; Kim, M.S.; GBD 2023 Substance Use Collaborators; Shin, J.I.; Yon, D.K. Global burden of amphetamine, cannabis, cocaine and opioid use in 204 countries, 1990–2023: A Global Burden of Disease Study. Nat. Med. 2026, 32, 527–544, . [CrossRef]
- Degenhardt, L.; Charlson, F.; Ferrari, A.; Santomauro, D.; Erskine, H.; Mantilla-Herrara, A.; Whiteford, H.; Leung, J.; Naghavi, M.; Griswold, M.; et al. The global burden of disease attributable to alcohol and drug use in 195 countries and territories, 1990–2016: A systematic analysis. Lancet Psychiatry 2018, 5, 987–1012, . [CrossRef]
- Volkow, N.D.; Koob, G.F.; McLellan, A.T. Neurobiologic advances from the brain disease model of addiction. N. Engl. J. Med. 2016, 374, 363–371, . [CrossRef]
- Volkow, N.D.; Blanco, C. Substance use disorders: A comprehensive update of classification, epidemiology, neurobiology, clinical aspects, treatment and prevention. World Psychiatry 2023, 22, 203–229, . [CrossRef]
- Bennett, T.; Holloway, K.; Farrington, D.P. The statistical association between drug misuse and crime: A meta-analysis. Aggress. Violent Behav. 2008, 13, 107–118, . [CrossRef]
- Fazel, S.; Yoon, I.A.; Hayes, A.J. Substance use disorders in prisoners: An updated systematic review and meta-regression analysis in recently incarcerated individuals. Addiction 2017, 112, 1725–1739, . [CrossRef]
- Tomaz, V.; Moreira, D.; Souza Cruz, O. Criminal reactions to drug-using offenders: A systematic review of the effect of treatment and/or punishment on reduction of drug use and/or criminal recidivism. Front. Psychiatry 2023, 14, 935755, . [CrossRef]
- Beeler, S.; Gerrish, O.; Aldred, B.G.; BlackDeer, A.A. Histories of violence among clients seeking substance use disorder treatment: A systematic mapping review. Front. Psychiatry 2024, 15, 1307641, . [CrossRef]
- Darke, S. The toxicology of drug-related homicide. Drug Alcohol Rev. 2019, 38, 6–14, . [CrossRef]
- Lin, C.; Cousins, S.J.; Zhu, Y.; Clingan, S.E.; Mooney, L.J.; Kan, E.; Wu, F.; Hser, Y.-I. A scoping review of social determinants of health’s impact on substance use disorders over the life course. J. Subst. Use Addict. Treat. 2024, 166, 209484, . [CrossRef]
- Saladino, V.; Calaresi, D.; Petruccelli, F.; Verrastro, V. Reflections on recidivism and relapse prevention among Italian justice-involved juveniles: A general overview. Soc. Sci. 2024, 13, 254, . [CrossRef]
- Park, S. A societal exploration of drug crime consequences. Addiction & Criminology 2023, 6, 176, . [CrossRef]
- Bonta, J.; Andrews, D.A. The Psychology of Criminal Conduct, 7th ed.; Routledge: New York, NY, USA, 2024.
- Montanari, L.; Royuela, L.; Mazzilli, S.; Vandam, L.; Alvarez, E.; Llorens, N.; Carapinha, L.; Grohmannova, K.; Isajeva, L.; Ignataviciute, L.; et al. Prevalence of drug use before and during imprisonment in seven European countries (2014–2018). J. Community Psychol. 2024, 52, 1015–1030, . [CrossRef]
- Laudet, A.B. The road to recovery: Where are we going and how do we get there? Empirically driven conclusions and future directions for service development and research. Subst. Use Misuse 2008, 43, 2001–2020, . [CrossRef]
- Cloud, W.; Granfield, R. Conceptualizing recovery capital: Expansion of a theoretical construct. Subst. Use Misuse 2008, 43, 1971–1986, . [CrossRef]
- Kelly, J.F.; Greene, M.C.; Bergman, B.G. Beyond abstinence: Changes in indices of quality of life with time in recovery in a nationally representative sample of U.S. adults. Alcohol. Clin. Exp. Res. 2018, 42, 770–780, . [CrossRef]
- Wright, S.; Williams, R.; Finkelstein, N. Effectiveness of reentry programs for people with substance use disorders. Subst. Abuse Treat. Prev. Policy 2014, 9, 45, . [CrossRef]
- Agenția Națională Antidrog. Raport Național Privind Situația Drogurilor 2023; Agenția Națională Antidrog: Bucharest, Romania, 2023. Available online: https://ana.gov.ro/wp-content/uploads/2025/01/RAPORT-NATIONAL-PRIVIND-SITUATIA-DROGURILOR_2023.pdf (accessed on 3 January 2026).
- Turcu, T.-A.; Lescaie, A.; Grama, A.R.; Strătulă, A.-C.; Vincene, A.-I.; Grigoraș, L.-M.; Jităreanu, C.; Babeu, A.M.; Gafencu, M.; Crăciun, M.-D.; et al. Patterns and emerging trends in acute poisoning with substances of abuse used for recreational purposes in adolescents: A six-year multicentre study. Life 2024, 14, 1033, . [CrossRef]
- European Union Drugs Agency (EUDA). European Drug Report 2025: Trends and Developments—Harm Reduction. Table EDR25-HR-5: Availability of Drug-Related and Other Health and Social Care Interventions Targeting People Who Use Drugs and Are in Prison, EU+2, 2023; EUDA: Lisbon, Portugal, 2025. Available online: https://www.euda.europa.eu/publications/european-drug-report/2025/harm-reduction_en (accessed on 3 January 2026).
- Sandelowski, M. Whatever happened to qualitative description? Res. Nurs. Health 2000, 23, 334–340, . [CrossRef]
- Sandelowski, M. What’s in a name? Qualitative description revisited. Res. Nurs. Health 2010, 33, 77–84, . [CrossRef]
- Neergaard, M.A.; Olesen, F.; Andersen, R.S.; Sondergaard, J. Qualitative description—the poor cousin of health research? BMC Med. Res. Methodol. 2009, 9, 52, . [CrossRef]
- Tong, A.; Sainsbury, P.; Craig, J. Consolidated criteria for reporting qualitative research (COREQ): A 32-item checklist for interviews and focus groups. Int. J. Qual. Health Care 2007, 19, 388–396, . [CrossRef]
- Lincoln, Y.S.; Guba, E.G. Naturalistic Inquiry; Sage Publications: Newbury Park, CA, USA, 1985.
- Birt, L.; Scott, S.; Cavers, D.; Campbell, C.; Walter, F. Member checking: A tool to enhance trustworthiness or merely a nod to validation? Qual. Health Res. 2016, 26, 1802–1811, . [CrossRef]
- Braun, V.; Clarke, V. Using thematic analysis in psychology. Qual. Res. Psychol. 2006, 3, 77–101, . [CrossRef]
- Saunders, B.; Sim, J.; Kingstone, T.; Baker, S.; Waterfield, J.; Bartlam, B.; Burroughs, H.; Jinks, C. Saturation in qualitative research: Exploring its conceptualization and operationalization. Qual. Quant. 2018, 52, 1893–1907, . [CrossRef]
- Nowell, L.S.; Norris, J.M.; White, D.E.; Moules, N.J. Thematic analysis: Striving to meet the trustworthiness criteria. Int. J. Qual. Methods 2017, 16, . [CrossRef]
- Kiger, M.E.; Varpio, L. Thematic analysis of qualitative data: AMEE Guide No. 131. Med. Teach. 2020, 42, 846–854, . [CrossRef]
- Braun, V.; Clarke, V. One size fits all? What counts as quality practice in (reflexive) thematic analysis? Qual. Res. Psychol. 2021, 18, 328–352, . [CrossRef]
- Miech, R.A.; Johnston, L.D.; Patrick, M.E.; O’Malley, P.M.; Bachman, J.G.; Schulenberg, J.E. Monitoring the Future National Survey Results on Drug Use, 1975–2022: Secondary School Students; Monitoring the Future Monograph Series; Institute for Social Research, University of Michigan: Ann Arbor, MI, USA, 2023. Available online: https://monitoringthefuture.org/results/publications/monographs (accessed on 1 February 2026).
- Das, P.; Das, T.; Roy, T.B. Social jeopardy of substance use among adolescents: A review to recognize the common risk and protective factors at the global level. Psychoactives 2023, 2, 113–132, . [CrossRef]
- Volkow, N.D.; Boyle, M. Neuroscience of addiction: Relevance to prevention and treatment. Am. J. Psychiatry 2018, 175, 729–740, . [CrossRef]
- Elbur, A.I.; Suprasert, B.; Mirzazadeh, A.; Wilson, E.C.; McFarland, W. Hooked before the first injection: The role of prescription opioids in early injection drug use initiation in San Francisco. Addict. Behav. Rep. 2026, 23, 100706, . [CrossRef]
- Cheng, H.; Chamratrithirong, A.; Miller, B.A. Beginning the Thai Family Matters Project: An areal analysis of bad neighborhoods and adolescents’ problematic behaviors in Thailand. J. Youth Adolesc. 2006, 35, 1075–1087, . [CrossRef]
- Heilig, M.; Epstein, D.H.; Nader, M.A.; Shaham, Y. Time to connect: Bringing social context into addiction neuroscience. Nat. Rev. Neurosci. 2016, 17, 592–599, . [CrossRef]
- Austin, A.; Favril, L.; Craft, S.; Thliveri, P.; Freeman, T.P. Factors associated with drug use in prison: A systematic review of quantitative and qualitative evidence. Int. J. Drug Policy 2023, 122, 104248, . [CrossRef]
- Rhodes, T. The ‘risk environment’: A framework for understanding and reducing drug-related harm. Int. J. Drug Policy 2002, 13, 85–94, . [CrossRef]
- Leasure, P.; Boehme, H.M. An experimental investigation examining the impact of medical association statements about drug addiction on perceptions of criminal culpability and punishment. Soc. Sci. 2024, 13, 373, . [CrossRef]
- Heyman, G.M. Addiction: A Disorder of Choice; Harvard University Press: Cambridge, MA, USA, 2009.
- Koob, G.F.; Volkow, N.D. Neurobiology of addiction: A neurocircuitry analysis. Lancet Psychiatry 2016, 3, 760–773, . [CrossRef]
- Stellern, J.; Xiao, K.B.; Grennell, E.; Sanches, M.; Gowin, J.L.; Sloan, M.E. Emotion regulation in substance use disorders: A systematic review and meta-analysis. Addiction 2023, 118, 30–47, . [CrossRef]
- Rada, C.; Lunga, R.-A. Emotion regulation difficulties and coping strategies in substance use disorders: Effects of severity, impulsivity, and social support in a clinical sample. Psychiatry Int. 2026, 7, 150, . [CrossRef]
- Miller, J.; Drake, E.; Nafziger, M. What Works to Reduce Recidivism by Drug Offenders?; Washington State Institute for Public Policy: Olympia, WA, USA, 2016. Available online: https://www.wsipp.wa.gov/ (accessed on 1 February 2026).
- Solbakken, L.E.; Bergvik, S.; Wynn, R. Breaking down barriers to mental healthcare access in prison: A qualitative interview study with incarcerated males in Norway. BMC Psychiatry 2024, 24, 288, . [CrossRef]
- Best, D.; Hennessy, E.A. The science of recovery capital: Where do we go from here? Addiction 2022, 117, 1139–1145, . [CrossRef]
- Marceau, K. The role of parenting in developmental trajectories of risk for adolescent substance use: A bioecological systems cascade model. Front. Psychol. 2023, 14, 1277419, . [CrossRef]
- Russ, A.J.; Bullo, A.; Schulz, P.J. Do parental communication and monitoring counteract substance use in adolescents? A scoping review of dyadic studies. Health Commun. 2026, 41, 800–849, . [CrossRef]
- Pinquart, M.; Reeg, A. Associations of parental monitoring and behavioral control with substance use in adolescents and emerging adults: A meta-analysis. Subst. Use Misuse 2025, 60, 1497–1505, . [CrossRef]
- Goldstein, P.J. The drugs/violence nexus: A tripartite conceptual framework. J. Drug Issues 1985, 15, 493–506, . [CrossRef]
- Lunga, R.A.; Rada, C.; Neagu, A.E.; Marinescu, V.; Rodideal, A.A. Substance use and violence in adolescence: Emotional and relational dynamics. Anthropological Researches and Studies 2026, 16, 1–20, https://www.journalstudiesanthropology.ro/wp-content/uploads/2026/02/x1-2026-ARS-Lunga-et-al-Substance-LAST-AD-RL-.pdf (accessed on 10 March 2026). [CrossRef]
- Yang, M.; Mamy, J.; Gao, P.; Xiao, S. From abstinence to relapse: A preliminary qualitative study of drug users in a compulsory drug rehabilitation center in Changsha, China. PLoS ONE 2015, 10, e0130711, . [CrossRef]
- Best, D.; Laudet, A. The Potential of Recovery Capital; RSA: London, UK, 2010.
- Davidson, L.; Nelson, A. Strength training as recovery capital in substance use disorders. Journal of Mental Health and Social Behaviour 2025, 7, 201, . [CrossRef]
- Gregory, V.L., Jr.; Wilkerson, D.A.; Wolfe-Taylor, S.N.; Miller, B.L.; Lipsey, A.D. Digital cognitive-behavioral therapy for substance use: Systematic review and meta-analysis of randomized controlled trials. Am. J. Drug Alcohol Abuse 2024, 50, 771–785, . [CrossRef]
- Marlatt, G.A.; Donovan, D.M. Relapse Prevention: Maintenance Strategies in the Treatment of Addictive Behaviors, 2nd ed.; Guilford Press: New York, NY, USA, 2005.
- Lomas, C. Neurobiology, psychotherapeutic interventions, and emerging therapies in addiction: A systematic review. J. Addict. Dis. 2024, 44, 14–32, . [CrossRef]
- Duncan, J.; Stansfield, R.; Hall, S.; O’Connor, T. Women’s engagement with humanist, spiritual and religious meaning-making in prison: A longitudinal study of its impact on recidivism. Religions 2018, 9, 171, . [CrossRef]
- Strauss, T.; Swerin, D.D.; Rodgers, K. Establishing Continuity of Care: A Report on the Terry Reilly Health Services Mentally Ill Offender Community Transition Program; Idaho Statistical Analysis Center, Idaho State Police: Meridian, ID, USA, 2022. Available online: https://justiceresearch.dspacedirect.org/server/api/core/bitstreams/741e3ec4-4ebd-41ce-b1e1-5f756cac94d1/content (accessed on 10 February 2026).
- Chandler, R.K.; Fletcher, B.W.; Volkow, N.D. Treating drug abuse and addiction in the criminal justice system: Improving public health and safety. JAMA 2009, 301, 183–190, . [CrossRef]
- Olver, M.E.; Stockdale, K.C.; Wormith, J.S. A meta-analytic review of the predictive validity of the risk–needs–responsivity model. Crim. Justice Behav. 2014, 41, 529–563, . [CrossRef]
- Livingston, J.D.; Milne, T.; Fang, M.L.; Amari, E. The effectiveness of interventions for reducing stigma related to substance use disorders: A systematic review. Addiction 2012, 107, 39–50, . [CrossRef]
- Ferrer-Pérez, C.; Montagud-Romero, S.; Blanco-Gandía, M.C. Neurobiological theories of addiction: A comprehensive review. Psychoactives 2024, 3, 35–47, . [CrossRef]
- Guvernul României. Hotărârea Guvernului nr. 186 din 27 Februarie 2025 Privind Organizarea și Funcționarea Agenției Naționale pentru Politici și Coordonare în Domeniul Drogurilor și al Adicțiilor; Monitorul Oficial al României, nr. 184; Guvernul României: Bucharest, Romania, 2025. Available online: https://legislatie.just.ro/public/DetaliiDocument/295120 (accessed on 10 January 2026).
| Theme (Results) | Recovery Capital Domain [20] | Polarity |
| 3.1. Initiation factors and vulnerabilities associated with onset | Social/Community | Deficit (negative capital) |
| 3.2. Clinical and psychological manifestations of use | Human/Physical | Deficit (negative capital) |
| 3.3. Experience of dependence and withdrawal | Physical | Deficit (negative capital) |
| 3.4. Cognitive and social mechanisms sustaining use | Human | Deficit (negative capital) |
| 3.5. Family: risk factor, protective factor, and source of suffering | Social | Ambivalent (resource and deficit) |
| 3.6. Recovery, abstinence, and identity reconstruction | Human + Social + Cultural | Resource (positive, emergent capital) |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2026 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).