2. Methods
2.1. Study Design
A pre–post pilot educational study was conducted to evaluate the effect of a structured educational program on participants’ knowledge, attitudes, and reported use of evidence-based practice. The study was developed as part of the AISPO (Italian Association for Solidarity among Peoples) international cooperation project “Support to Public Health Services for Women and Children in the Red Sea, Kassala and Khartoum States” — SESAMAI, AID 12513 — which aimed to strengthen maternal and child healthcare services in Sudan. Because of the ongoing security situation in Sudan and the impossibility for the Italian teaching team to travel to the country safely, the educational program was specifically designed and delivered through a synchronous online learning format. This approach ensured continuity of training activities despite travel restrictions and security-related constraints, while maintaining direct interaction between participants and instructors.
The educational program was designed to be consistent with the Classification Rubric for EBP Assessment Tools in Education (CREATE) framework [
12]. The CREATE framework provides a taxonomy for classifying EBP educational assessment tools according to the five steps of EBP: ask, search, appraise, integrate, and evaluate, and according to different educational outcome domains, including reaction to the educational experience, attitudes, knowledge, and skills. In this study, CREATE was used not only as a reference framework for assessment but also as a pedagogical structure to organize the training contents, practical exercises, and final applied activities.
2.2. Questionnaires Used for the Pre-Post Study
The pre–post assessment was conducted using two self-administered evidence-based practice (EBP) questionnaires. Nursing students completed the Evidence-Based Practice Competence Questionnaire (EBP-COQ) [
13], while registered nurses completed the Evidence-Based Practice Competency Questionnaire for Professionals (EBP-COQ Prof©) [
14]. Both instruments were administered at baseline during the first part of the first lesson and repeated upon completion of the educational program, following the final practical activity. Prior to their use, formal authorization was obtained from the original authors, and a use agreement was signed. The EBP-COQ is a 25-item questionnaire developed to assess undergraduate nursing students’ self-perceived EBP competence across three dimensions: attitudes, skills, and knowledge. In its original validation, the instrument showed good internal consistency, with a Cronbach’s alpha of 0.888 for the total scale and values of 0.940, 0.756, and 0.800 for the three subscales, respectively. The three-factor structure explained 55.55% of the variance.
The EBP-COQ Prof© is a 35-item questionnaire designed for registered nurses and evaluates four dimensions of EBP competency: attitudes, knowledge, skills, and utilization. In the original validation study, the instrument demonstrated good psychometric properties, with Cronbach’s alpha values ranging from 0.817 to 0.948 across dimensions and adequate construct validity supported by exploratory and confirmatory factor analyses.
Both questionnaires were translated into Sudanese Arabic through a forward-translation process conducted by a cultural mediator. The translated versions subsequently underwent a first-round content and face-validity assessment.
Content validity was evaluated by a panel of six registered nurses who independently rated the relevance and clarity of each item using a 4-point scale. Overall, reviewers considered both the EBP-COQ and EBP-COQ Prof© appropriate for the target population. However, several linguistic refinements were recommended to improve clarity and conceptual equivalence with the original instruments. In particular, some EBP-related technical terms were replaced with more commonly used expressions in Sudanese Arabic, ambiguous wording was simplified, and selected items were rephrased to better convey the intended meaning. Reviewers also highlighted that respondents with limited previous exposure to EBP might experience difficulties understanding questions related to EBP concepts and research terminology.
Face validity was assessed separately among six nursing students using the EBP-COQ. Although the questionnaire was generally considered understandable, students reported difficulty interpreting several items. Based on their feedback, the translation of “critical appraisal” was revised from a literal translation to a more explanatory expression reflecting the process of systematically evaluating research evidence. Additional modifications included clarifying items 17, 23, 24, and 25 through simpler wording and sentence restructuring. Furthermore, the reverse-worded item “I prefer to avoid reading scientific articles” was rephrased to reduce potential misunderstanding associated with negative sentence construction. Minor spelling corrections and linguistic adjustments were also implemented throughout both questionnaires to improve readability and consistency.
Following these revisions, both questionnaires underwent a second round of expert review. The revised versions demonstrated satisfactory content validity, with item-level Content Validity Index (I-CVI) values exceeding the recommended threshold of 0.80 for all items in both the EBP-COQ and EBP-COQ Prof©. The final Sudanese Arabic versions were therefore considered linguistically clear, culturally appropriate, and conceptually equivalent to the original instruments and were subsequently administered to participants enrolled in the educational program. Internal consistency was assessed using Cronbach’s alpha coefficient on baseline (pre-intervention) data. The EBP-COQ Professional Competence Scale demonstrated excellent reliability, with an overall Cronbach’s alpha of 0.912, indicating a high degree of internal consistency among the items.
The Evidence-Based Practice Questionnaire for Nursing Students showed acceptable overall internal consistency, with a Cronbach’s alpha of 0.663. Although lower than that observed for the EBP-COQ Professional Competence Scale, this value suggests a moderate level of reliability within the study sample.
In addition to the questionnaire items, participants were asked to provide socio-demographic and professional information. For nursing students, data included age, gender, year of study, and previous participation in EBP-related training. For registered nurses, information collected included age, gender, educational level, years of professional experience, clinical area of practice, and previous EBP training.
2.3. Setting
The study was conducted at Comboni College in Port Sudan, located in north-eastern Sudan, in the Red Sea State. Comboni College of Science and Technology is a higher education institution originally located in Khartoum, Sudan, that was forced to relocate to Port Sudan due to the ongoing armed conflict. The College offers several academic programs, including a Bachelor of Science in Nursing. The College served as local partner in the educational and research program. The College provided a dedicated meeting room equipped with tables and chairs suitable for lectures and group-based activities. The room had internet access, a slide-projection screen and screen-sharing capability, audio speakers, and a meeting microphone that enabled interaction between participants and remote teachers. A movable camera was positioned on the screen and oriented toward the meeting room, enabling remote teachers to observe participants’ activities and interact with them during the sessions. The room was ventilated and equipped with air conditioning and fans to ensure a comfortable learning environment during the sessions, particularly considering the high local temperatures and the number of participants attending the lessons in the same room.
Ten internet-enabled laptop computers were available for the training activities. Based on this availability, the maximum number of participants was set at 30, with an average ratio of three participants per laptop.
2.4. Participants and Sampling
A purposive sample of 29 participants was recruited. The sample included registered nurses and Bachelor Degree in Nursing students. The students were enrolled in the Bachelor's Degree in Nursing program at Comboni College, while the registered nurses came from various hospitals and community healthcare services in the Red Sea State area who were mainly engaged in maternal and child health, consistent with the international cooperation project's focus on these two health fields. The educational initiative was disseminated through Comboni College, and participation was based on an expression of interest. The final sample consisted of the 29 nursing students and registered nurses who responded to the call and volunteered to participate in the educational program. The inclusion of both nursing students and professionals was based on the educational needs identified in the local context. In particular, research methodology and EBP are not systematically or extensively included in nursing education and professional training pathways. Therefore, the program was designed to provide both students and registered nurses with foundational and applied competencies in nursing research methodology and evidence-based practice.
2.5. Educational Framework and Program Structure
The educational program was structured according to the CREATE framework [
12]. This framework was used to align the learning objectives, teaching strategies, practical exercises, and assessment methods with the main dimensions of EBP learning. In line with CREATE, the program addressed the five core steps of EBP: asking answerable clinical or research questions, searching for the best available evidence, appraising evidence, integrating evidence into practice, and evaluating its application.
The program also targeted several CREATE educational outcome domains. Knowledge was addressed through theoretical lessons on research methodology, EBP principles, study designs, data collection, and evidence appraisal. Skills were developed through practical exercises, including literature searches, database construction, basic statistical analysis, qualitative data analysis, and evidence synthesis. Attitudes and self-efficacy were addressed through guided discussion, reflection, and teach-back activities to strengthen participants’ confidence in using EBP in clinical contexts. Behavioral change was promoted through the final applied activity, in which participants developed an internal protocol on kangaroo mother care to support the translation of evidence into local clinical practice.
This structure is consistent with the CREATE framework, which distinguishes among different levels of EBP learning, from learners’ reactions and attitudes to knowledge, skills, behaviors, and potential patient benefits. The framework also emphasizes the importance of linking assessment methods to learner characteristics, learning aims, and the specific EBP steps addressed by the educational intervention.
2.6. Educational Intervention
Participants attended a synchronous distance educational program delivered through Microsoft Teams (version 26120.3106.4725.800). The program consisted of 40 hours of training. Teaching hours were scheduled according to Central European Time (CET). Due to the time difference, sessions initially corresponded to 10:00 a.m.–2:00 p.m. in Sudan; after the standard time change in Italy, the sessions corresponded to 9:00 a.m.–1:00 p.m. in both Italy and Sudan. Most sessions lasted 4 hours. The only exception was the final training module, which consisted of 16 hours delivered over three consecutive days: one full 8-hour day and two morning sessions from 9:00 a.m. to 1:00 p.m.. Each session included an intermediate break to allow participants to rest from the lesson, recover energy by eating, and have time for prayer, in accordance with participants’ needs and the local cultural and religious context.
The training took place weekly between March and May 2026. The weekly schedule was intentionally adopted to allow participants time to reflect on, internalize, and consolidate the contents addressed during each session before attending the next one. Access to the lessons was provided through a Microsoft Teams link sent by email to Comboni College.
All teaching materials, including slides, exercises, and supporting documents, were uploaded to a shared Google Drive folder before each lesson to facilitate participants’ access. The folder also included the reference bibliography for the course. Access to the shared folder was restricted to participants and educational staff, including teachers, facilitators, and the cultural mediator.
2.7. Teaching Team
The educational program was delivered by a team of Italian nursing researchers. Two nurse research fellows alternated in teaching activities and ensured continuity throughout the course. One teacher was a female nurse researcher with a PhD, while the other was a male nurse researcher and PhD student.
In addition, a female nurse with expertise in pediatric, maternal, and child healthcare and holding a Master’s Degree in Nursing and Midwifery Sciences was invited to participate in the educational program. Her contribution was particularly relevant for providing practical examples and clinical applications of the theoretical content. This allowed the program to maintain a close connection between research methodology, EBP, and the broader objectives of the international cooperation project in maternal and child healthcare.
2.8. Language, Translation, and Cultural Mediation
All lessons were delivered in English and translated into Sudanese Arabic by a cultural mediator with a Bachelor Degree in English Language and Literature. The translation process was further supported by a local physician, who assisted and facilitated the mediator in clarifying specific medical, nursing, and healthcare-related terminology. This approach was adopted to facilitate participants’ understanding and to ensure that technical concepts were accurately conveyed within the local linguistic and cultural context.
2.9. Educational Intervention Contents
The contents of the educational program were organized according to the five EBP steps described in the CREATE framework [
Figure 1].
First, the “Ask” component focused on the definition of EBP, the identification of clinical and research problems, and the formulation of answerable research questions. Participants were guided in translating practical problems into structured questions suitable for evidence searching.
Second, the “Search” component focused on identifying and retrieving the best available evidence. Participants were trained to search MEDLINE via PubMed, to use keywords and Boolean operators, and to identify relevant quantitative and qualitative studies.
Third, the “Appraise” component addressed the critical appraisal of evidence. Participants were introduced to quantitative and qualitative research designs, data collection methods, basic statistical concepts, and the interpretation of research findings. They also worked on the appraisal of papers retrieved during practical exercises.
Fourth, the “Integrate” component focused on the translation of evidence into practice. Participants were guided in synthesizing evidence and considering how research findings could be applied to local clinical needs, with particular attention to maternal and child healthcare.
Finally, the “Evaluate” component was addressed through reflection, feedback, teach-back activities, and the final development of an internal protocol on kangaroo mother care. This final activity allowed participants to apply the full EBP process, from question formulation to evidence synthesis.
The main topics included in the program are summarized in Table 1 and include: principles of EBP and evidence-based nursing; formulation of research questions; literature searching in MEDLINE via PubMed; quantitative methodology; data collection; basic statistical analysis and database construction using Microsoft Excel; qualitative methodology; interviews and focus groups; content analysis; and the Van Kaam method modified by Moustakas.
2.10. Practical Exercises and Group Work
The program combined theoretical lessons with practical exercises. After the theoretical component of each lesson, participants engaged in group-based activities lasting approximately 20–30 minutes each. These exercises were designed to consolidate the contents covered during the session and to support the acquisition of practical EBP skills.
Participants were divided into three groups of approximately 10 members each. Groups were balanced in terms of number of participants and composition, including both registered nurses and nursing students, gender, and expertise in maternal and pediatric areas. When computer-based activities were required, such as literature searching, database construction, basic statistical analysis, or qualitative data analysis, each group had access to three computers. This organization allowed all participants to practice the use of computers and digital tools during the exercises.
Feedback was provided through the evaluation of practical activities and through the teach-back method. During the lessons, teachers used guiding questions to recall previously addressed concepts, verify understanding, and stimulate reflection on the EBP process. These strategies were intended to reinforce knowledge, support self-efficacy, and promote the gradual development of EBP-related skills.
Table 1.
Educational Intervention Contents using the CREATE framework.
Table 1.
Educational Intervention Contents using the CREATE framework.
| Dates |
Programme |
CREATE framework component |
Main content |
Teaching and learning activities |
Time |
Teaching team |
| Wednesday, 04 March 2026 |
Initial assessment |
Baseline assessment of EBP attitudes, knowledge, skills, self-efficacy, and use |
Initial assessment of participants’ EBP-related knowledge and competences |
Administration of the pre-test questionnaires:
- -
EBP-COQ Prof©
- -
EBP-COQ
|
Before the lesson (about 30 min before) |
- -
Cultural mediator
- -
Two nurse research fellows (PhD, PhD student
- -
Registered Nurse with expertise in pediatric, maternal, and child healthcare (MScN)
|
| Training module 1 part 1 |
Foundation for all CREATE steps |
Foundations of research methodology |
- -
Types of study designs and the evidence pyramid
|
2 hours |
Training module 1 Part 2 |
Ask |
Searching for best evidence: framing the research question |
Structuring the research question |
2 hours |
| Thursday, 26 March 2026 |
Training module 2 |
Search |
Searching for best evidence using MEDLINE via PubMed |
Building a search strategy based on the structured question (from module no. 1) and running the search in MEDLINE via PubMed |
4 hours |
| Thursday, 02 April 2026 |
Training module 3 |
Appraise Evaluate
|
How to collect quantitative data |
How to collect quantitative data (examples related to: physiological changes in pregnancy; pregnancy nutrition—micro/macro nutrients; anaemia prevention; prevention of maternal complications: hypertension, infections, bleeding). Reliability of the data collection method |
4 hours |
| Wednesday, 08 April 2026 |
Training module 4 |
Appraise |
Quantitative data analysis |
- Descriptive analysis - Correlations |
4 hours |
| Wednesday, 15 April 2026 |
Training module 5 |
Appraise Integrate Evaluate
|
How to collect qualitative data |
- -
Interviews
- -
Focus groups
- -
Field notes
|
4 hours |
| Wednesday, 22 April 2026 |
Training module 6 |
Appraise Integrate
|
Phenomenological qualitative data analysis How to analyse qualitative data |
Van Kaam Method as adapted by Moustakas and Content Analysis |
4 hours |
| 5–7 May 2026 |
Training Module 7 |
Ask, Search, Appraise, Integrate, Evaluate |
Development of an internal protocol on kangaroo mother care |
Participants formulated a research question, searched MEDLINE via PubMed, critically appraised retrieved papers, synthesized evidence, and developed a protocol on the use, benefits, indications, and precautions of kangaroo mother care |
16 hours |
| After completion of the training |
Final assessment |
Post-intervention assessment of EBP attitudes, knowledge, skills, self-efficacy, and use |
Final assessment of participants’ EBP-related knowledge and competences |
Administration of the post-test questionnaires:
- -
EBP-COQ Prof©
- -
EBP-COQ
|
After the lesson (about 30min after) |
2.11. Final Activity
The educational program concluded with three practical meetings focused on the development of an internal protocol on kangaroo mother care. These meetings were mainly guided by the nurse with expertise in maternal and child healthcare.
During this final activity, participants worked in groups to develop a protocol that could be applied and implemented within their own clinical units. The protocol focused on the use, benefits, indications, and precautions related to kangaroo mother care. To develop the protocol, participants formulated a research question, searched the literature in MEDLINE via PubMed, critically appraised the retrieved papers, and synthesized the available evidence to answer the research question.
Both quantitative and qualitative studies emerged during the literature search. These studies were used not only to support protocol development but also to reinforce previously addressed course contents. Through teach-back activities, participants were encouraged to revisit and apply key concepts related to EBP, research methodology, critical appraisal, and evidence synthesis.
2.12. Access to Materials
All synchronous lessons were video-recorded. Recordings included the teacher facilitation from Milan, the classroom in Port Sudan, and the slides presented during each session. After each lesson, the video recording was uploaded to the shared Google Drive folder, allowing participants to review the contents and listen to the lessons again after the synchronous session.
2.13. Ethical Aspects
This pre–post pilot study was conducted in accordance with the principles of the Declaration of Helsinki. Before implementation, the training activities were formally communicated to and approved by the competent local health authority. In the study setting, the Ministry of Health and Social Development also acts as the ethical approving authority. Accordingly, the Director of the Health Sector Office of the Ministry of Health and Social Development, Red Sea State, Sudan, issued an official no-objection and approval letter for the educational program, reference no. 44/B/1, dated 23 February 2026. Participation in the educational activities and related evaluation procedures was voluntary. Participants were informed about the purpose of the training and the use of aggregated data for scientific and educational purposes. No clinical interventions were performed, and no biological samples or identifiable clinical records were collected. Data were analyzed and reported anonymously and in aggregate form to ensure participants’ confidentiality.
2.14. Statistical Analysis
Data were analyzed using IBM SPSS Statistics version 29 (IBM Corp., Armonk, NY, USA). Descriptive statistics were used to summarize participants’ socio-demographic and professional characteristics. Continuous variables were reported as means and standard deviations (SD), whereas categorical variables were presented as frequencies and percentages.
For both the EBP-COQ and EBP-COQ Prof©, total and domain scores were calculated according to the scoring procedures described by the original authors.
Prior to inferential analyses, the normality of pre–post difference scores was evaluated using the Shapiro–Wilk test. To evaluate changes in EBP-related competencies following the educational intervention, pre- and post-intervention scores were compared using paired-samples t-tests. Separate analyses were conducted for nursing students (EBP-COQ) and registered nurses (EBP-COQ Prof©). Differences were examined for both total questionnaire scores and individual domain scores.
For statistically significant comparisons, effect sizes were calculated using Cohen’s d for paired samples and interpreted according to conventional thresholds as small (0.20), medium (0.50), and large (0.80). Mean differences and corresponding 95% confidence intervals (95% CI) were also calculated to quantify the magnitude and precision of the observed changes.
All statistical tests were two-tailed, and a p-value < 0.05 was considered statistically significant.