Submitted:
29 June 2026
Posted:
30 June 2026
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Abstract

Keywords:
1. Introduction
2. Materials and Methods
2.1. Study Design
2.2. Study Population
2.3. Sample Size Calculation
2.4. Variables and Measurement Instruments
2.4.1. Sociodemographic Variables and Personal History
2.4.2. Lifestyle Factors
2.4.3. Mediterranean Diet
2.4.4. Screen Addiction and Dependence Assessment
2.5. Statistical Analysis
2.6. Ethical Considerations
2.7. Use of Artificial Intelligence Tools
3. Results
4. Discussion
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Abbreviations
| APISAL | Primary Care Research Unit of Salamanca; |
| BMI | Body Mass Index; |
| CERV | Video Game-Related Experiences Questionnaire; |
| CIUS | Compulsive Internet Use Scale; |
| EDAS-18 | Smartphone Dependency and Addiction Scale, short 18-item version; |
| IBSAL | Institute of Biomedical Research of Salamanca; |
| IPAQ-SF / IPAQ | International Physical Activity Questionnaire—Short Form; |
| MEDAS / MEDAS-14 | Mediterranean Diet Adherence Screener; |
| MedDiet | Mediterranean Diet; |
| METs / MET | Metabolic Equivalent of Task; |
| OR | Odds Ratio; |
| PREDIMED | Prevention with Mediterranean Diet; |
| RICAPPS | Network for Research on Chronicity, Primary Care, and Health Promotion; |
| SACyL | Regional Health Management of Castile and León; |
| SD | Standard Deviation; |
| SE | Standard Error; |
| STROBE | Strengthening the Reporting of Observational Studies in Epidemiology; |
| VIF | Variance Inflation Factor; |
| WHO | World Health Organization. |
Appendix A
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| Variables and instruments |
Total sample (N = 496) |
Low adherence (MEDAS < 9; n = 339) |
High adherence (MEDAS ≥ 9; n = 157) |
p-valueᵃ |
| Age (years), mean ± SD | 26.60 ± 4.41 | 26.29 ± 4.53 | 27.28 ± 4.06 | 0.015* |
| Sex, n (%) | <0.001* | |||
| Male | 220 (44.4) | 171 (50.4) | 49 (31.2) | |
| Female | 276 (55.6) | 168 (49.6) | 108 (68.8) | |
| Alcohol consumption (g/week), mean ± SD |
48.93 ± 73.90 | 52.19 ± 74.03 | 41.88 ± 73.36 | 0.149 |
| Physical activity (MET-min/week), mean ± SD |
2660.50 ± 2499.48 | 2623.46 ± 2739.65 | 2740.49 ± 1884.60 | 0.628 |
| Smoking status, n (%) | 0.002* | |||
| Non-smoker | 407 (82.1) | 266 (78.5) | 141 (89.8) | |
| Smoker | 89 (17.9) | 73 (21.5) | 16 (10.2) | |
| BMI (kg/m²), mean ± SD | 24.01 ± 3.80 | 24.30 ± 3.96 | 23.38 ± 3.35 | 0.008* |
| Digital addiction scales | ||||
| EDAS-18 (smartphone), mean ± SD |
40.87 ± 12.24 | 41.02 ± 12.63 | 40.57 ± 11.37 | 0.703 |
| CIUS (Internet), mean ± SD | 13.83 ± 9.89 | 13.57 ± 9.50 | 14.38 ± 10.70 | 0.418 |
| CERV (video games), mean ± SDᵇ | 3.54 ± 5.22 | 3.80 ± 5.29 | 2.98 ± 5.06 | 0.103 |
| Global digital addiction score, mean ± SD | 58.25 ± 21.76 | 58.39 ± 21.77 | 57.93 ± 21.80 | 0.826 |
| Variables and instruments | Men (n = 220) | Women (n = 276) | p-valueᵃ |
| Age (years), mean ± SD | 27.09 ± 4.40 | 26.22 ± 4.38 | 0.029* |
| Score mediterraneam diet, mean ± SD | 6.96 ± 2.06 | 7.81 ± 1.88 | <0.001* |
| Alcohol consumption (g/week), mean ± SD | 61.56 ± 91.54 | 38.86 ± 54.11 | 0.001* |
| Physical activity (MET-min/week), mean ± SD | 3172 ± 3140 | 2253 ± 1737 | <0.001* |
| Smoking status, n (%) | 0.413 | ||
| Non-smoker | 184 (83.6) | 223 (80.8) | |
| Smoker | 36 (16.4) | 53 (19.2) | |
| BMI (kg/m²), mean ± SD | 25.30 ± 3.67 | 22.98 ± 3.59 | <0.001* |
| Digital Addiction Scales | |||
| EDAS-18 (smartphone) | 40.37 ± 12.15 | 41.28 ± 12.31 | 0.411 |
| CIUS (internet) | 13.38 ± 9.75 | 14.18 ± 10.01 | 0.370 |
| CERV (video games) | 5.94 ± 6.18 | 1.63 ± 3.23 | <0.001* |
| Global digital addiction | 59.69 ± 22.09 | 57.09 ± 21.46 | 0.187 |
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