Submitted:
15 March 2026
Posted:
17 March 2026
You are already at the latest version
Abstract
Keywords:
1. Introduction
2. Materials and Methods
2.1. Study Design and Data Sources
2.2. NoSQL-Oriented Data Architecture
2.3. Data Cleaning and Analytic Sample
2.4. Variables
2.5. External Country Stratification
2.6. Statistical Analysis
2.7. Software, Reproducibility, and Ethical Considerations
3. Results
3.1. Global Trends in Service Coverage and Financial Hardship
3.2. Main Association Between Service Coverage and Financial Hardship
3.3. Domain-Specific Associations
3.4. Inequalities by Wealth Quintile and Urbanization
3.5. Cross-Sectional Heterogeneity in Latest Available Values
3.6. Stratified Slopes, Convergence, and Country Typologies
4. Discussion
4.1. Strengths and Limitations
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
Abbreviations
| Abbreviation | Meaning | Abbreviation | Meaning |
| AI | artificial intelligence | CI | confidence interval |
| CICV | Centro de Investigaciones en Ciencias de la Vida | CSV | comma-separated values |
| OOP | out-of-pocket | FH | financial hardship |
| FH40 | financial hardship due to out-of-pocket health spending | GEE | generalized estimating equations |
| 95% CI | 95% confidence interval | WB | World Bank |
| JSON | JavaScript Object Notation | NoSQL | non-relational, document-oriented data architecture |
| ORCID | Open Researcher and Contributor ID | PNG | Portable Network Graphics |
| Q1 | poorest wealth quintile | Q5 | richest wealth quintile |
| RMNCH | reproductive, maternal, newborn, and child health | SCI | service coverage index |
| SD | standard deviation | SDG | Sustainable Development Goal |
| UHC | universal health coverage | WHO | World Health Organization |
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| Dataset | Raw observations | Countries/economies in raw file | Time span | Analytic filters |
|---|---|---|---|---|
| UHC service coverage index (SCI) | 24840 | 207 | 2000-2023 | Full index and four domain subindices |
| Financial hardship (FH40) | 17634 | 180 | 1985-2024 | All household types, total urbanization for overall panel; hardship subcomponents retained |
| Harmonized analytic panel | 981 | 159 | 2000-2023 | Country-year overlap between SCI and FH, continent assigned, and World Bank income group matched where available |
| Variable | Mean | SD | Median | IQR | Min | Max | N |
|---|---|---|---|---|---|---|---|
| SCI full index (0-100) | 65.63 | 16.04 | 70.0 | 19.0 | 14.0 | 88.0 | 981 |
| Financial hardship, all (%) | 20.53 | 12.43 | 16.52 | 15.61 | 0.0 | 77.45 | 981 |
| Large non-impoverishing OOP burden (%) | 3.67 | 2.47 | 3.11 | 3.16 | 0.0 | 15.85 | 959 |
| Impoverishing OOP expenditure (%) | 16.85 | 11.87 | 12.45 | 14.49 | 0.0 | 73.89 | 959 |
| Pushed into poverty (%) | 1.7 | 1.19 | 1.42 | 1.21 | 0.0 | 9.53 | 885 |
| Further impoverished (%) | 15.45 | 11.75 | 10.84 | 13.75 | 0.2 | 72.36 | 885 |
| Model | Beta | CI low | CI high | p-value | N | R2 |
|---|---|---|---|---|---|---|
| Pearson correlation | -0.722 | — | — | <0.001 | 981 | 0.521 |
| Country FE + trend | -0.447 | -0.691 | -0.203 | 0.0003 | 981 | 0.886 |
| Two-way FE | -0.441 | -0.707 | -0.175 | 0.0011 | 981 | 0.889 |
| Mixed model | -0.496 | -0.564 | -0.429 | <0.001 | 981 | — |
| GEE | -0.521 | -0.599 | -0.443 | <0.001 | 981 | — |
| Spline test | — | — | — | 0.0618 | 981 | 0.890 |
| SCI domain | Beta | CI low | CI high | p-value |
|---|---|---|---|---|
| RMNCH subindex | 0.12 | -0.133 | 0.373 | 0.3521 |
| Infectious diseases subindex | -0.206 | -0.336 | -0.076 | 0.0019 |
| Non-communicable diseases subindex | -0.257 | -0.506 | -0.007 | 0.0437 |
| Service capacity and access subindex | -0.076 | -0.172 | 0.019 | 0.1158 |
| Metric | Mean | SD | Median | IQR | Min | Max | N |
|---|---|---|---|---|---|---|---|
| Poorest-richest gap in financial hardship (Q1-Q5) | 53.73 | 21.40 | 53.81 | 31.57 | -28.91 | 99.75 | 1323 |
| Rural-urban gap in financial hardship | 12.50 | 12.02 | 9.88 | 14.90 | -34.30 | 53.23 | 783 |
| Continent | Countries | Mean SII | Median SII |
|---|---|---|---|
| Africa | 49 | 66.93 | 70.59 |
| Americas | 26 | 45.94 | 49.71 |
| Asia | 34 | 56.5 | 59.17 |
| Europe | 36 | 36.8 | 38.81 |
| Oceania | 11 | 20.36 | 20.49 |
| Income group | Countries | Mean SII | Median SII |
|---|---|---|---|
| High income | 44 | 35.73 | 35.38 |
| Upper-middle income | 45 | 46.51 | 43.38 |
| Lower-middle income | 48 | 60.13 | 70.14 |
| Low income | 24 | 68.85 | 70.29 |
| Continent | Countries | SCI mean | SCI median | FH mean | FH median |
|---|---|---|---|---|---|
| Africa | 49 | 49.06 | 47.0 | 31.29 | 32.44 |
| Oceania | 11 | 60.45 | 62.0 | 5.96 | 5.38 |
| Asia | 36 | 68.08 | 69.5 | 21.25 | 22.16 |
| Americas | 27 | 74.48 | 77.0 | 17.51 | 15.91 |
| Europe | 36 | 77.94 | 77.5 | 11.57 | 11.38 |
| Income group | Countries | SCI mean | SCI median | FH mean | FH median |
|---|---|---|---|---|---|
| High income | 41 | 80.05 | 81.00 | 11.49 | 11.00 |
| Upper-middle income | 45 | 71.64 | 71.00 | 16.83 | 14.64 |
| Lower-middle income | 47 | 56.91 | 56.00 | 24.39 | 26.02 |
| Low income | 24 | 42.21 | 42.00 | 36.36 | 36.02 |
| Continent | Beta | CI low | CI high | p-value |
|---|---|---|---|---|
| Africa | -0.495 | -0.779 | -0.211 | 0.0006 |
| Americas | -0.223 | -0.741 | 0.294 | 0.3977 |
| Asia | -0.333 | -0.675 | 0.009 | 0.0567 |
| Europe | -0.175 | -0.689 | 0.339 | 0.5047 |
| Oceania | 0.062 | -0.298 | 0.422 | 0.7344 |
| Income group | Beta | CI low | CI high | p-value |
|---|---|---|---|---|
| High income | -0.021 | -0.383 | 0.341 | 0.9090 |
| Upper-middle income | -0.336 | -0.856 | 0.184 | 0.2059 |
| Lower-middle income | -0.295 | -0.968 | 0.379 | 0.3911 |
| Low income | -1.002 | -1.673 | -0.330 | 0.0035 |
| Outcome | Baseline coefficient | CI low | CI high | p-value | R2 |
|---|---|---|---|---|---|
| SCI annual slope | -0.019 | -0.022 | -0.016 | <0.001 | 0.487 |
| FH annual slope | -0.031 | -0.041 | -0.022 | <0.001 | 0.260 |
| Cluster | Profile | Countries | SCI (latest) | FH all (latest) | SCI annual slope | FH annual slope | Mean Q1-Q5 gap |
|---|---|---|---|---|---|---|---|
| A | High coverage; low hardship | 53 | 73.81 | 11.90 | 0.54 | -0.08 | 36.40 |
| B | Low coverage; rapid gains; high inequality | 35 | 46.14 | 34.37 | 1.37 | -0.91 | 65.65 |
| C | Fragile; rising hardship | 6 | 37.33 | 37.90 | 0.63 | 1.79 | 33.91 |
| D | Mid-high coverage; persistent inequality | 37 | 70.92 | 22.57 | 0.48 | -0.40 | 67.87 |
| Country | Continent | SCI (latest) | FH all (latest) |
|---|---|---|---|
| United States | Americas | 88.0 | 6.81 |
| United Kingdom | Europe | 88.0 | 7.47 |
| Korea, Rep. | Asia | 87.0 | 9.65 |
| Finland | Europe | 86.0 | 10.15 |
| Switzerland | Europe | 86.0 | 10.31 |
| Japan | Asia | 86.0 | 11.0 |
| Israel | Asia | 85.0 | 16.57 |
| Netherlands | Europe | 84.0 | 3.17 |
| Germany | Europe | 84.0 | 4.8 |
| Slovenia | Europe | 84.0 | 6.05 |
| Country | Continent | SCI (latest) | FH all (latest) |
|---|---|---|---|
| Congo, Dem. Rep. | Africa | 39.0 | 60.03 |
| Burundi | Africa | 45.0 | 56.64 |
| Central African Republic | Africa | 33.0 | 52.97 |
| Sierra Leone | Africa | 42.0 | 47.89 |
| Nigeria | Africa | 47.0 | 47.35 |
| Liberia | Africa | 42.0 | 43.29 |
| Malawi | Africa | 55.0 | 43.02 |
| Bangladesh | Asia | 54.0 | 41.7 |
| Mali | Africa | 41.0 | 40.07 |
| Sudan | Africa | 46.0 | 39.92 |
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