Submitted:
26 February 2026
Posted:
28 February 2026
You are already at the latest version
Abstract
1,4-Dimethoxy-2,3-dinitrobenzene (1) reduction using sodium hydrosulfite gave 3,6-dimethoxybenzene-1,2-diamine (2) and 3,6-dimethoxy-2-nitroaniline (3) in 24% and 59% yield respectively. The nitroaniline 3 was acetylated with acetyl chloride to give N-(3,6-dimethoxy-2-nitrophenyl)acetamide (4) in 65% yield and with acetic anhydride to give N,N’-(3,6-dimethoxy-2-nitrophenyl)diacetamide (5) in 78% yield. Novel compounds 4 and 5 were characterized by FT-IR, 1H and 13C-NMR, and HRMS. The X-ray crystal structure of acetamide 4 is presented.
Keywords:
aniline
; benzoquinone
; nitrobenzene
; reduction
; sodium dithionate
Copyright: This open access article is published under a Creative Commons CC BY 4.0 license, which permit the free download, distribution, and reuse, provided that the author and preprint are cited in any reuse.
