Background/Objectives: Caring for a child with Autism Spectrum Disorder (ASD) is often associated with elevated psychological distress and reduced life satisfaction. Mindfulness-based interventions may offer substantial benefits by enhancing emotional regulation, reducing maladaptive cognitive patterns, and strengthening mindful parenting. This randomized controlled trial (RCT) examined the effectiveness of an eight-week Mindfulness-Based Cognitive Therapy (MBCT) program, enriched with mindful parenting practices, on parental mental health and parent-reported child behavior outcomes. Methods: Fifty-six parents of children with ASD were randomly assigned to an MBCT intervention group (n = 30) or a waitlist-control group (n = 26). Participants completed assessments at baseline (T0), post-intervention (T1), and one-month follow-up (T2), including the DASS-21, PANAS, and SWLS. Parents rated the overall severity of their child’s behavior problems to explore indirect treatment effects. Results: All participants receiving MBCT (100%) completed the program successfully and reported high acceptability. At baseline, no significant differences were observed between groups. Compared to controls, the MBCT group demonstrated significant reductions in depression, anxiety, and stress, alongside increases in positive affect and life satisfaction at T1. These improvements were further strengthened or maintained at T2. However, the control group showed no significant changes across time. Additionally, parents in the MBCT group reported indirect improvements in their children’s behavioral adjustment at T1 and T2. Conclusions: Findings demonstrate that MBCT constitutes an effective intervention for reducing parental psychopathology and indirectly enhancing child positive behavior, emphasizing the importance of incorporating mindfulness and mindful parenting components into family-centered interventions for parents of children with ASD.