Submitted:
15 September 2025
Posted:
17 September 2025
You are already at the latest version
Abstract
Keywords:
Evidence Before This Study
Added Value of This Study
Implications of All the Available Evidence
Background
Rationale
Methods
Study Design and Participants
Data Collection
Data Analysis
Ethics
Results
Clinical Care Inequities
“Yeah, I went to them before for HRT cause likely it was definitely menopausal and even confirmed it was an bloods that but because it was moods that I was concerned about because I was snapping at my husband and I was really, I was more worried about that, then it was the antidepressant that was offered” PID12
"And I actually was so mentally unwell that I thought that I was going crazy and I was suicidal... And I was given antidepressants and beta blockers and diazepam and all sorts. No one even considered that this could be hormones. I wasn’t even perimenopausal apparently... until someone actually listened to me and gave me HRT, and within a week I felt like myself again." PID13
Structural and Systemic Barriers
“I went to the GP four or five times, but every time they said it’s just stress or anxiety… I kept saying I think it's something else, but they just gave me sleeping tablets or said try yoga. I felt completely dismissed." PID26
"When I started having symptoms at 30, they didn’t believe it was menopause. I was told I was too young, that it was probably just depression or PMS. No one mentioned HRT until years later." PID33
"Living in rural Scotland meant my GP didn’t really know what to do… I had to wait nearly eight months before I saw someone who actually specialised in menopause. In the meantime, I was struggling to function at work." PID46
"It took me nearly a year before I found someone who actually linked my brain fog and mood swings to menopause. Before that, I thought I was just losing my mind. My GP kept brushing it off as stress."
"I eventually went private because I just couldn’t take it anymore. I felt guilty because I know not everyone can afford it. It shouldn’t have to come down to money just to be taken seriously and feel better." PID17
"I paid for a private consultation after being messed about for months. It was the first time anyone actually listened and understood. But why should it be this way? It’s not fair. People with less money are just left to suffer." PID5
"The only way to get an appointment was through the e-consult, but by the time I finished work or looked after my mum, it was closed. I’d try in the morning and it would say all slots were gone. I just gave up some days." PID24
"I live quite far out and the internet’s patchy, so trying to do these online forms is a nightmare. And English isn’t my first language, so half the time I’m not sure what they’re even asking." PID5
Workplace Inequities and Policy Deficits
"I was forgetting things constantly, zoning out in meetings, and struggling to keep up. My manager said I might need to be moved to a lower banding. I didn’t even know it was menopause until months later. No one mentioned it, and there was no policy to protect me." PID23
"I was a senior midwife, but I had to step down. Between the hot flushes, bladder issues, and brain fog, I just couldn’t keep up with the pace. There was no flexibility, no understanding. I felt like I had no choice but to leave." PID44
"I had to leave the NHS. My memory was shot, I was crying at work, and nobody knew what to do with me. They sent me to occupational health, but even they didn’t understand menopause properly. I lost a job I loved because of ignorance." PID40
"My line manager was amazing, she let me adjust my hours when the insomnia got really bad. But that was just her being kind, not because there was a policy. If she wasn’t there, I don’t know what I’d have done." PID29
"We had a menopause café at work, which helped me feel less alone. But I learned more from Facebook groups and charity websites than from any official NHS resource. There’s just no consistent support—depends on where you work and who’s in charge."PID41
Cross-Cutting Inequalities
"I went into menopause at 30. Nobody talked to me about what that would mean—not for my health, not for my future, not for my fertility. I was grieving, but there was no space for that grief anywhere in the system." PID33
"After chemo and the oophorectomy, everything just stopped. I wasn’t offered counselling, no one explained the menopause side of things. I couldn’t take HR
T because of the cancer, but there were no other options. Work didn’t get it either—they just saw me as unreliable."PID42
"They ignored my pain for years, then suddenly it was all too late. I had surgery and woke up in menopause. I didn’t get a chance to plan, to think about kids. That decision was taken out of my hands, and no one helped me process that."PID49
Discussion
Clinical-level Implications
Population-Level Implications
Policy-Level Implications
Conclusion
Funding
Conflicts of interest
Availability of data and material
Code availability
Author contributions
Ethics approval
Consent to participate
Consent for publication
Acknowledgements: MARIE Consortium
References
- Local Government Association. Menopause Factfile [Available from: https://local.gov.uk/our-support/workforce-and-hr-support/wellbeing/menopause/menopause-factfile.
- Greendale GA, Lee NP, Arriola ER. The menopause. The Lancet. 1999;353(9152):571-80.
- Sherman S. Defining the menopausal transition. The American journal of medicine. 2005;118(12):3-7. [CrossRef]
- McKinlay SM, Brambilla DJ, Posner JG. The normal menopause transition. Maturitas. 1992;14(2):103-15.
- Delanerolle G, Phiri P, Elneil S, Talaulikar V, Eleje GU, Kareem R, et al. Menopause: a global health and wellbeing issue that needs urgent attention. The Lancet Global Health. 2025;13(2):e196-e8. [CrossRef]
- El Khoudary SR, Aggarwal B, Beckie TM, Hodis HN, Johnson AE, Langer RD, et al. Menopause transition and cardiovascular disease risk: implications for timing of early prevention: a scientific statement from the American Heart Association. Circulation. 2020;142(25):e506-e32. [CrossRef]
- Than S, Moran C, Beare R, Vincent A, Lane E, Collyer TA, et al. Cognitive trajectories during the menopausal transition. Frontiers in dementia. 2023;2:1098693. [CrossRef]
- Lobo RA, Gompel A. Management of menopause: a view towards prevention. The Lancet Diabetes & Endocrinology. 2022;10(6):457-70. [CrossRef]
- Than S, Moran C, Beare R, Vincent AJ, Collyer TA, Wang W, et al. Interactions between age, sex, menopause, and brain structure at midlife: a UK Biobank study. The Journal of Clinical Endocrinology & Metabolism. 2021;106(2):410-20. [CrossRef]
- Kalita K, Raina D, Mall P. The Basics of Perimenopause: Menopause and Pre-Menopause. Utilizing AI Techniques for the Perimenopause to Menopause Transition: IGI Global; 2024. p. 1-25.
- Hamoda H, Moger S, Morris E, Baldeweg S, Kasliwal A, Gabbay F, et al. Menopause practice standards. Post Reproductive Health. 2022;28(3):127-32. [CrossRef]
- Sharman Moser S, Chodick G, Bar-On S, Shalev V. Healthcare utilization and prevalence of symptoms in women with menopause: a real-world analysis. International journal of women's health. 2020:445-54. [CrossRef]
- CIPD Media Centre. Over a quarter of women say menopause has had a negative impact on career progression. 2023.
- Almeida L. Menopause ‘pension penalty’ costs women £30,000 in retirement. The Telegraph. 2023.
- Crown Office & Procurator Fiscal Service. Menopause policy equality impact assessment. 2023.
- Westwood S. ‘GP services are still heteronormative’: Sexual minority cisgender women’s experiences of UK menopause healthcare–Health equity implications. Post Reproductive Health. 2024;30(4):225-31.
- Eder C, Roomaney R. Transgender and non-binary people’s experience of endometriosis. Journal of Health Psychology. 2025;30(7):1610-23. [CrossRef]
- Nowaskie DZ, Menez O. Healthcare experiences of LGBTQ+ people: non-binary people remain unaffirmed. Frontiers in Sociology. 2024;9:1448821. [CrossRef]
- Lumsden MA, Davies M, Sarri G. Diagnosis and management of menopause: the National Institute of Health and Care Excellence (NICE) guideline. JAMA internal Medicine. 2016;176(8):1205-6.
- Daniel K, Bousfield J, Hocking L, Jackson L, Taylor B. Women’s Health Hubs: a rapid mixed-methods evaluation. Health and Social Care Delivery Research. 2024;12(30):1-138. [CrossRef]
- Group A-WMTaF. All-Wales Menopause Task and Finish Group, Final Report, January 2023. Welsh Government; 2023.
- Office for National Statistics. Ethnic group, England and Wales: Census 2021.
- The King's Fund. What are health inequalities? 2025 [Available from: https://www.kingsfund.org.uk/insight-and-analysis/long-reads/what-are-health-inequalities?
- National Institute for Health and Care Research. NIHR publishes framework to promote race equality in public involvement in research 2022 [Available from: https://www.nihr.ac.uk/news/nihr-publishes-framework-promote-race-equality-public-involvement-research?

| PID | Menopause Stage | Menopause Type | HRT Use | Testosterone | GP Use | Gynaecology Use | Employment Status | Country |
|---|---|---|---|---|---|---|---|---|
| PID01 | Perimenopause | Natural | Yes | Yes | Yes | No | Employed | England |
| PID02 | Menopause | Natural | Yes | No | Yes | No | Employed | England |
| PID03 | Postmenopause | Surgical | Yes | No | Yes | No | Employed | England |
| PID04 | Menopause | Natural | Yes | No | Yes | No | Employed | England |
| PID05 | Perimenopause | Natural | Yes | No | Yes | No | Employed | England |
| PID06 | Menopause | Natural | Yes | No | Yes | No | Employed | England |
| PID07 | Menopause | Natural | Yes | No | Yes | No | Employed | England |
| PID08 | Menopause | Natural | Yes | Yes | Yes | No | Employed | England |
| PID09 | Menopause | Natural | Yes | Yes | Yes | No | Employed | England |
| PID10 | Menopause | Natural | Yes | No | Yes | No | Employed | England |
| PID11 | Postmenopause | Surgical | Yes | No | Yes | No | Employed | England |
| PID12 | Menopause | Natural | Yes | No | Yes | No | Employed | England |
| PID13 | Menopause | Natural | Yes | No | Yes | No | Employed | England |
| PID14 | Menopause | Natural | No | No | Yes | No | Employed | England |
| PID15 | Menopause | Natural | Yes | Yes | Yes | No | Employed | England |
| PID16 | Perimenopause | Natural | No | No | Yes | No | Employed | England |
| PID17 | Perimenopause | Natural | No | No | Yes | No | Employed | England |
| PID18 | Perimenopause | Natural | Yes | No | Yes | No | Employed | England |
| PID19 | Menopause | Natural | Yes | No | Yes | No | Employed | England |
| PID20 | Perimenopause | Natural | Yes | No | Yes | No | Employed | England |
| PID21 | Menopause | Natural | No | No | Yes | No | Employed | England |
| PID22 | Perimenopause | Natural | Yes | No | Yes | No | Employed | England |
| PID23 | Postmenopause | Natural | Yes | Yes | Yes | Yes | Employed | England |
| PID24 | Menopause | Natural | Yes | No | Yes | No | Employed | England |
| PID25 | Menopause | Natural | Yes | No | Yes | No | Employed | England |
| PID26 | Postmenopause | Natural | Yes | Yes | Yes | Yes | Employed | England |
| PID27 | Menopause | Natural | Yes | No | Yes | No | Employed | England |
| PID28 | Menopause | Natural | Yes | Yes | Yes | No | Employed | England |
| PID29 | Menopause | Natural | No | No | Yes | No | Employed | England |
| PID30 | Menopause | Natural | Yes | No | Yes | No | Employed | England |
| PID31 | Postmenopause | Natural | Yes | No | Yes | No | Employed | England |
| PID32 | Postmenopause | Natural | No | No | Yes | No | Unemployed | England |
| PID33 | Menopause | Natural | Yes | Yes | No | Employed | England | |
| PID34 | Postmenopause | Natural | Yes | Yes | Yes | No | Employed | England |
| PID35 | Menopause | Natural | Yes | No | Yes | No | Unemployed | England |
| PID36 | Postmenopause | Natural | Yes | No | Yes | No | Unemployed | England |
| PID37 | Menopause | Natural | Yes | No | Yes | Yes | Employed | Scotland |
| PID38 | Postmenopause | Natural | Yes | No | Yes | No | Unemployed | England |
| PID39 | Postmenopause | Natural | Yes | No | Yes | No | Employed | England |
| PID40 | Postmenopause | Surgical | No | No | Yes | No | Employed | England |
| PID41 | Perimenopause | Natural | No | No | Yes | No | Employed | England |
| PID42 | Postmenopause | Natural | Yes | No | Yes | No | Employed | England |
| PID43 | Perimenopause | Surgical | Yes | No | Yes | No | Employed | England |
| PID44 | Menopause | Medical | Yes | No | Yes | No | Employed | England |
| PID45 | Perimenopause | Natural | Yes | No | Yes | No | Employed | England |
| PID46 | Menopause | Natural | Yes | No | Yes | No | Employed | Scotland |
| PID47 | Menopause | Surgical | Yes | No | Yes | Yes | Employed | England |
| PID48 | Perimenopause | Not stated | No | No | Yes | No | Employed | England |
| PID49 | Postmenopause | Not stated | Yes | No | Yes | No | Unemployed | England |
| PID50 | Perimenopause | Natural | Yes | Yes | Yes | No | Unemployed | England |
| Theme | Sub-theme | Illustrative Quote |
|---|---|---|
| Clinical Inequities | Delayed diagnosis | ‘I didn’t know what was happening for years. It was brushed off as stress.’ (PID37) |
| Clinical Inequities | Limited access to HRT | ‘I was told I couldn’t have HRT because of my medical history, but no alternatives were offered.’ (PID46) |
| Clinical Inequities | Misdiagnosis of menopausal symptoms | ‘They said it was depression and gave me antidepressants, but it was menopause all along.’ (PID38) |
| Clinical Inequities | Fragmented care pathways | ‘I was bounced between departments—nobody seemed to own my care.’ (PID40) |
| Clinical Inequities | Inappropriate prescribing | ‘They gave me HRT patches that worsened my symptoms, and nobody reviewed it.’ (PID45) |
| Structural Inequities | Inadequate GP training | ‘My GP didn’t even consider menopause until I brought it up.’ (PID47) |
| Structural Inequities | Lack of menopause-informed services | ‘There’s no one-stop clinic or specialist menopause team where I live.’ (PID44) |
| Structural Inequities | Poor workplace policy | ‘I had no support at work and ended up quitting because of the symptoms.’ (PID39) |
| Structural Inequities | Geographic disparities in care | ‘You get better menopause care in the city—rural areas are forgotten.’ (PID46) |
| Structural Inequities | Lack of public health communication | ‘No one talks about this stuff publicly—it’s like a secret.’ (PID33) |
| Socioeconomic Inequalities | Cost-related barriers to HRT | ‘I had to pay for private treatment because the NHS wouldn’t help.’ (PID50) |
| Socioeconomic Inequalities | Workplace discrimination | ‘I was seen as unreliable because I couldn’t focus—I lost my job.’ (PID40) |
| Socioeconomic Inequalities | Poverty and housing insecurity | ‘When you’re choosing between food and prescriptions, menopause isn’t a priority.’ (PID34) |
| Socioeconomic Inequalities | Limited digital access | ‘Online menopause services are no good when you don’t have Wi-Fi.’ (PID48) |
| Socioeconomic Inequalities | Reliance on informal networks | ‘I learnt more from my friends than from doctors.’ (PID38) |
| Recommendation | Description | Supporting Evidence/Policy Context |
|---|---|---|
| Re-establish Women’s Health Hubs | Set up regional, integrated services offering streamlined menopause care, including diagnostics and treatment | Evidence indicated in this study coupled with the England’s Women’s Health Strategy aiming to improve access and outcomes through community-based hubs |
| Implement culturally competent toolkits than generic support tools | Provide healthcare professionals to improve patient care | Developed by multidisciplinary experts and patients-public, as the MARIE consortium |
| Adopt BMA-style workplace menopause policies | Encourage organisations to implement policies that normalise discussions, offer reasonable adjustments, and reduce stigma | British Medical Association model policy fosters a safe, informed, and supportive workplace culture |
| Mandate menopause action plans for large employers | Require employers to develop menopause support plans under upcoming legislation to normalize menopause in workplace settings | Evidence indicated in this study coupled with the Employment Rights Bill, aiming to embed menopause into employer best practice |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2025 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).