Drones have become valuable tools in wildlife research due to their ability to access remote areas and collect high-resolution data with minimal human interference. However, their increasing use raises concerns about potential disturbances to wildlife. This review synthesizes existing research on the impacts of drone disturbances across terrestrial, aerial, and aquatic species, focusing on operational factors, sensory stimuli, species-specific sensitivities, and physiological and behavioral responses. Findings indicate that drone flight altitude, speed, approach distance, and noise levels significantly influence wildlife reactions, with some species exhibiting increased vigilance, flight responses, or physiological stress. Additionally, visual stimuli and environmental conditions shape species' perception of drones, affecting their disturbance thresholds. While short-term behavioral changes have been widely documented, the long-term effects of repeated drone exposure remain poorly understood. This paper underscores the importance of continuing research into drone-wildlife interactions, emphasizing the importance of minimizing disturbances through optimized flight parameters and technological advancements. Future research should focus on developing species-specific guidelines and mitigation strategies to balance conservation efforts with the responsible use of drone technology.