Vaccination Coverage and Predictors of Vaccination Among Children Aged 12-23 Months in the Pastoralist Communities of Ethiopia: A Mixed Methods Design

1. Introduction

Immunization remains one of the most important public health interventions and is a cost-effective strategy for reducing both the morbidity and mortality associated with infectious diseases. Over two million deaths are delayed through immunization each year worldwide [1,2]. Despite this, vaccine-preventable diseases remain the most common cause of childhood mortality, with an estimated three million deaths each year in Africa [3,4]. Moreover, a well-functioning immunization system is one of the key elements of a strong health system and prepares a country for future health challenges. In fact, immunization coverage is used as an indicator to assess health system capacity and primary health care access. Investing human, technical and financial resources in immunization builds the capacity to deliver primary health care services and ensure that no child’s life is jeopardized by a vaccine-preventable disease [5].

After six years of establishment by the WHO in 1974, Ethiopia launched its Expanded Program on Immunization (EPI) in 1980 to reduce mortality, morbidity and disability in children and mothers from vaccine-preventable diseases [6]. When the program started, the target groups included children under two years of age until it changed to infants and mothers in 1986 to align with the global immunization targets [7]. Since 2019, the primary targets for immunization services in Ethiopia include infants, children between the ages of one and two years for the measles conjugate vaccine (MCV2), girls between the ages of nine and 14 years for the human papillomavirus (HPV) vaccine, and women in the reproductive age group, which is part of the implementation of immunization as a life-course approach. There is an established immunization program support system in the country starting from the federal level down to the health post [8].

With the gradual increase in the incidence of Ethiopia since 2011, the current administrative coverage, as reported in the WHO and United Nations Children's Fund (UNICEF) estimates of national immunization coverage revised in 2022, reached 89% for BCG, 98% and 93% for diphtheria-pertussis-tetanus (DPT) 1% DPT3, respectively, 88% for polio, and 89% and 82% for MCV1 and MCV3, respectively [9,10]. A systematic review and meta-analysis study conducted in Ethiopia from    to 2019 revealed that the pooled full immunization coverage in Ethiopia was 58.92%, and the trend of immunization coverage improved from time to time, but there were great disparities among different regions.

According to the Ethiopian Demographic and Health Survey (EDHS), there has been steady progress in EPI coverage over the years. The percentage of children aged 12-23 months who received all basic vaccinations increased from 20% in 2005 and 24% in 2011 to 39% in 2016 and 44% in 2019. Additionally, the proportion of children who were not vaccinated decreased from 24% in 2005 to 19% in 2011 [11]. Despite substantial progress in Ethiopia vaccination efforts, disparities in vaccination coverage persist, particularly in underserved and remote regions such as the Afar region of Ethiopia. According to the annual report from the MOH, pentavalent and measles vaccination coverage was low and below the expected targets in the Afar region [12,13]. The percentage of children aged 12-35 months who did not have a vaccination card seen during the home visit was very high in Afar (85.1%), and the lowest percentage had a vaccination history at health facilities in Afar; the percentage who received at least one vaccination at a health facility was 26.2%. The Afar region is a percentage pastoralist community characterized by unique sociodemographic and geographical features, including a predominantly pastoralist population, limited access to healthcare services, and harsh environmental conditions. These factors can significantly impact healthcare-seeking behaviors, vaccine accessibility, and healthcare delivery strategies in the region [14]. Additionally, access to healthcare services is limited, and infrastructure barriers pose significant challenges to vaccine delivery and uptake.

Various studies conducted in different countries have shown that obstetric factors, maternal literacy, maternal knowledge, maternal attitude, having at least two ANC follow-ups, postnatal check-ups within two months after birth, place of birth and short distances from vaccination sites were significantly associated with complete immunization [9,10]^. Previous studies have examined vaccination coverage and predictors of immunization uptake in different regions of Ethiopia. However, there is limited existing research conducted in Afar that overlooks the unique sociocultural, economic, and geographical factors that may influence vaccination behaviour in this context. Moreover, unlike many previous studies that may have relied solely on quantitative approaches, this study employs a parallel mixed methods design, incorporating both quantitative and qualitative methods. This methodological approach enhances the robustness of the findings by triangulating data from different sources and providing a deeper understanding of the factors influencing full immunization in Afar contexts. Therefore, there is a clear gap in the literature regarding the determinants of vaccination among children in the Afar region. Consequently, this study aims to fill the gap left by previous studies by providing both qualitative and quantitative research. Therefore, this study aimed to assess vaccination coverage, the dropout rate and associated factors among children aged 12-23 months residing in the Afar Region, Ethiopia.

2. Materials and Methods

2.1. Study Area and Design and Population

The study was conducted in the Elidar, Dubti, and Gerani woredas of the Afar region. The Afar region is one of the regional state administrations in Ethiopia, with 34 woredas. Semera town is the regional capital of the Afar region, which is 591 kilometers from Addis Ababa. A community-based cross-sectional study design was used to undertake the quantitative study. A descriptive qualitative study design approach was used for the qualitative study. The three districts have a total population size of 232,033. Elidar has 105070, Dubti (85575), and Gerani (42388). All mothers/caretakers who have children 12-23 months of age in selected woredas of the Afar region were selected. All mothers/caretakers who had children who fulfilled the inclusion criteria were selected by a simple, random sampling technique during the data collection period. Mothers/caretakers who had children 12-23 months of age and who were found in their home during the data collection period and who resided for at least one year in the study area were eligible for the study. The study was conducted between December 2023 and January 2024.

2.2. Sample Size Determination and Sampling Procedure

For the quantitative part, the sample size of the evaluation was determined using a single population proportion formula considering the objectives of the baseline study of the project. To obtain the maximum sample size, 50% of the immunization among 12–23-month-old children was taken with a 95% level of certainty and a 5% margin of error. Considering a 10% non-response rate, the final sample size was 419. The samples were distributed in proportion to their population size to three districts. For the qualitative part, a total of nine key informant interviews (KIIs) were conducted among woreda health office EPI focal persons, health care workers (HCWs) and health extension workers (HEWs).

This sample was withdrawn from the three identified districts; in each district, three to four kebeles, the smallest administrative units in Ethiopia, were randomly selected using the WHO-recommended survey strategy approach for immunization. Once the kebeles were identified, the Gote/Villages were mapped. In the village, all candidate households (12-23 months and mother/father/caretaker pairs) were listed using data from HEWs, and simple random sampling approaches were used to select study participants. The sample was distributed to each district based on the population size (Elidar=190, Dubti=155 and Gerani=74). For the qualitative part, a purposive sampling procedure was used to obtain FGDs and KIIs study participants.

2.3. Study Variables and Operational Definitions

In this study, immunization coverage was a dependent variable. Additionally, the independent variables were the sociodemographic characteristics of mothers (age, residence, marital status, education status, occupation, partners’ education status, total family size), maternal health care utilization status, and mothers’ knowledge of immunization, and the child-related variables included the number of live births, sex of index child, age of indexed child in months, order of indexed child, index childbirth condition, and index child living with partner. Full immunization coverage: Calculated when a child has received the BCG vaccine, three doses of pentavalent, three doses of oral polio, three doses of PCV, two doses of Rota, a dose of IPV and one dose of measles before the age of one year [15].

2.4. Data Collection and Management

For the quantitative part, data were collected using a questionnaire adopted from the WHO, Ethiopian Demographic Health Survey (EDHS) and other pertinent literature and then translated into Amharic. Mothers or caretakers were asked to present vaccination records for an indexed (a child included in the study) child. The information about vaccination was then copied into the study instrument (questionnaire). Additionally, BCG scars were also checked on the child’s body. If a mother or caretaker reported that her child did not have a vaccination card, she was asked questions that were intended to be answered about the child's vaccination. Different strategies, such as the site of vaccination given (oral, injection and scar), the age at which the child received a specific vaccine, and the ability to distinguish routine vaccination schedules from campaign vaccination, were provided by the data collectors to help mothers/caretakers remember the vaccine taken by the children and to minimize recall bias. The household heads were interviewed based on the structured questionnaire. The data were collected electronically using the mobile applications Open Data Kits (ODK) and Kobo, where a structured questionnaire with pre-coded answers was uploaded.

The qualitative part of the study was addressed using KIIs. KIIs were performed among HCWs, HEWs and health development armies. A semi structured interview guide was used to facilitate in-depth interviews with the key informants to obtain insightful qualitative information on key issues to be examined in this baseline study. The interviews were facilitated by two individuals, one as a facilitator and the other serving as a note taker. All interviews were tape recorded after consent was obtained from each participant. Key informants were selected purposively based on their experience with the EPI program.

To ensure the data quality of the study, the team used highly consulted, client-approved and pretested data collection tools developed through reviewing relevant literature/national standards. In addition, the recruitment of experienced data collectors and supervisors considered their ability to speak the local language of the study sites. The training was conducted with the aim of developing a common understanding of the study objective and tools.

2.5. Data Processing and Analysis

The data were cleaned and transferred to SPSS version 25 for further analysis. The quantitative data from the community survey were summarized using descriptive statistics. A comparison of selected indicators was performed using relevant analysis criteria. Factors associated with vaccinations were assessed using binary logistic regression. Independent variables with a p value < 0.20 were candidates for inclusion in the multivariable logistic regression analysis. In the final model, a statistically significant association with the vaccination status of the children was declared using p values less than 0.05, and a 95% confidence interval (CI) of the AOR was considered in all cases.

The qualitative data were transcribed verbatim in local languages and translated to English by language experts. Then, the translated material was read to understand the importance of the material. Finally, the transcribed and translated data were analyzed via thematic analysis.

3. Results

A total of 419 sampled children aged 12-23 months were included, for a response rate of 100%.

3.1. Sociodemographic Characteristics of Respondents

The majority of the sampled children were from the Elidar woreda (45.3%), followed by Dubti (36.8%). More than three-quarters of the participants resided in rural areas (328, 78.3%). More than two-thirds of mothers (142, 33.9%) were in the age range of 22-25 years, followed by those aged ≥ 30 years (117, 27.9%). Almost all respondents were married (408, 97.4%), and most of the respondents were unable to read and write (345, 82.3%). Regarding religion, more than three-quarters of respondents (79%) were Muslim and were housewives (331, 79%). Concerning household economic status, most respondents reported their economic status as able to meet basic needs (343, 81.9%), followed by being unable to meet basic needs without charity (52, 12.4%) (Table 1).

3.2. Child Characteristics

Under three-quarters of mothers had a gravidity of less than or equal to four (302, 72.1%). Similarly, more than three-quarters (332, 79.2%) of them had a parity of less than or equal to four. More than half (235, 56.1%) of the children were males. The mean age of the index children was 16.7 months, with a standard deviation of 4.05 months. Almost one-third of the children (127, 30.3%) were in the age range of 12-13 months, followed by those in the age range of 21-23 months (103, 24.6%) (Table 2). All the children had mothers as their primary caretaker (419, 100%).

Almost three-quarters (313, 74.7%) of respondents heard about childhood vaccines. Two hundred and eighty seven (90.7%) participants mentioned that vaccination is important for protecting children from diseases, and participants also mentioned that vaccination is advantageous for healthy children (224, 71.6%). On the other hand, respondents also mentioned the disadvantages of vaccines. More than two-thirds (67%) of them reported that vaccines have side effects and that vaccines may make children sick (56.9%) (Table 3).

3.3. Factors Related to Vaccine Refusal and Vaccination Service Satisfaction

Regarding vaccine refusal, 52 (21.8%) respondents had a history of vaccine refusal for different reasons. Among the reasons included being given too many vaccines during the vaccination visit (28, 53.8%), a history of child illness after vaccination (26, 50%), and fear of injection pain (21, 40.4%). The least mentioned reason for refusal was mothers’ or caretakers’ misunderstanding that a single immunization qualifies as full vaccination (4, 7.7%). Fear, doubts, and suspicions about vaccines were reported among a small number of respondents (27, 8.6%), while the majority of mothers and caretakers did not have doubts or suspicions about vaccines (278, 88.8%). The reasons for fear, doubts or suspicions about vaccines were vaccination’s side effects (15, 55.6%), vaccinations that can make children sick (8, 29.6%), vaccinations that can sterilize children (2, 7.4%) and other factors, such as politics and religious concerns (2, 7.4%). Most of the respondents had good attitudes toward vaccines, as the study participants reported receiving vaccine recommendations to other community members (271, 86.6%).

The study participants reported different reasons for dissatisfaction; of these, the most common reasons mentioned were inaccessible vaccination services (90, 88.2%), vaccination site closed/vaccinator absent (67, 65.7%), no available vaccine at the vaccination sites (55, 53.9%) and long waiting times (58, 56.9%) (See Figure 1).

3.4. Maternal Health Service

Over half of the mothers (240, 57.3%) had at least one ANC follow-up, and nearly two-thirds (143, 59.6%) had no more than three ANC visits. Almost two-thirds of ANC visits were in health centres (152, 63.3%). Most of the mothers were informed about child vaccination during their ANC follow-up (Table 4). More than half of the children (227, 54.2%) were born at home. Regarding post-natal check-ups, only one-quarter (103, 24.9%) had check-ups after birth. Most of them were informed about vaccination during post-natal check-ups (97, 94.2%) (Table 5).

3.5. Vaccination Coverage

The overall percentage of children aged 12-23 months who had ever been vaccinated was 58.9% (n=247), with 95% CIs ranging from 54.2% to 63.7%. The percentages of children aged 12-23 months who had ever been vaccinated in Elidar were 71.6% (n=136), 46.1% (n=71) and 53.3% (n=40) in Dubti, Dubti and Gereni, respectively.

3.5.1. Proportion of Vaccination Based on Card Observation

The proportion of patients who received full vaccination via child vaccination cards was relatively greater at 70.7%, with corresponding 95% CIs ranging from 60.4% to 79.1% (n=65). The overall full vaccination status of all sampled children was 15.5%, with a 95% CI ranging from 12% to 19%. The dropout rate from Pentavelnt-1 to Pentavalent-3 was found to be 2.9% (n=12) (Table 6).

3.5.2. Proportion of Vaccination without Card Observation

The percentages of mothers or caretakers reporting vaccines in the absence of a vaccination card were 78.7% (n=122) for BCG, 56.2% (n=86) for three rounds of polio, 57.8% (n=85) for three rounds of pentavalent, 57.2% (n=83) for three rounds of PCV, 92.1%% (n=129) for two rounds of rota, 67.1% (n=104) for IPV and 92.9% (n=144) for measles (See Figure 2).

3.5.3. Proportion of Full Immunization

The proportion of full immunization for basic vaccines among children aged 12-23 months was found to be 25.1%, with a 95% CI ranging from 20.9%-29.2%. The proportion of full vaccination was not equal across the three districts. The proportion of full vaccination among rural children was 37.4% with a 95% CI of 30.5%-44.2% in Elidar, 25.3% with a 95% CI of 15.5%-35.2% in Gereni and 9.7% with a 95% CI of 5.1%-14.4% in Dubti. The proportion of measles among 15-month-old children was 111 (44.2%). The proportion of BCG scars according to the data collectors’ observations was 34.4% (n=144).

3.6. Barriers to Child Vaccination

Many different barriers were mentioned by the respondents; of these, the most common were not visiting the village (247, 58.9%), having a domestic workload (180, 43.0%), not accessing a vaccination service (155, 37%), having a closed/vaccinator vacancy at the vaccination site (153, 36.5%), having a long waiting time (138, 32.9%) and not receiving a vaccine at the vaccination site (106, 25.3%).

Regarding vaccine approval status, respondents revealed that most of the people around their community setting approved vaccination (308, 73.5%), vaccine approval was made by husbands/partners (301, 97.7%), followed by parents/parent in-laws (134, 43.5%) (Table 7).

The qualitative findings support that some of the key barriers to vaccination included the distance of the health facility, lack of health professional motivation, the desert weather conditions of Afar and community and partner engagement, which are some of the reasons for the low coverage of immunization.

Distance: Various KIIs stated that one of the reasons for low vaccination coverage is the long distance to the nearest health facility. The health center EPI focal person described the problem related to long distances to health facilities as follows:

"The health centre is far away from the majority of kebele residents. Thosecommunity members close to this health centre received frequent services from the institution, while those farther away from it did not often access the service. This scenario also applies toother health facilities in the region. Therefore, the long distance to the nearest health facility is the main barrier to EPI services.”

Similarly, the woreda EPI focal person emphasized long distances to the health center and other potential vaccination service sites, and a lack of transportation made the service inaccessible and unavailable to all parts of the region.

“The biggest problem fordesert or Berhama areassuch as the Afar region is the lack of health facilities, such as anearby health center, which makes vaccination services inaccessible andcreates problems in the supply of vaccines.”

The Dubti Woreda Health Office focal person described the impact of the COVID-19 pandemic on the routine EPI program;

“WhenCOVID-19 first began to spread in our nation, we had delays in implementing routine EPI delivery services. Later, whenthe COVID-19epidemic began to decline, we promptly resumed our normal EPI activities integrated withCOVID-19 prevention.”

Health workers’ motivation: All of the key informants highlighted reasons for low vaccination and the main challenges that prevent children from receiving vaccines.

“The major barriers tonot vaccinating children in our communities includea lack of commitment among health care workers, a shortage of EPI logistics and distribution,a lack of transportation access and high staff turnover.”

The Gereni Woreda Health Office EPI focal person stated the importance of motivating health workers as a lack of incentives and other motivating things that are not implemented. In addition, these health centres should be constructed because the number of health facilities in these areas is limited. Moreover, conflict is also mentioned as one of the reasons for low vaccination coverage.

“There is a lack of incentive for health workers, HEWs, and women's developmental army.The provision ofincentives is the best way to motivate people and increase the performance of activities. In our cases, we triedthis approach, and weachieved betterresults. However, itwas not enough and was not supported by health higher officials. In addition, our woreda isa geographically vast, populated, and repeatedly conflict-affected area. The woreda had only one health centre, which made it very distant from three health posts. This madeit very difficult to conduct the expected follow-up and support on EPI services across different catchment areas.Therefore, additional health centres should be constructed, and conflict issues should alsoreceive attention and should beresolved permanently.”

Program integration and partner engagement: Study participants also described the importance of integrating stakeholders and the need for governmental commitment to vaccination services. Informants from the woreda health office focal person and health centre EPI focal person spoke about this issue as follows:

“In this woreda vaccine service, delivery strategies are implemented only withthe initiative of NGOs, and this alone couldn’t solve our community’s problem at large. Therefore, itis essential to integrate woreda political leaders, community influential leaders and other concerned stakeholder leaders tobe involved in vaccine service delivery strategies.”

The Elidar Woreda Health Office focal person described partners involved in the immunization coverage program as well as areas of improvement in the potential collaboration of stakeholders.

Amref Health Africa isan NGO partner thatis engaged in promoting the expansion of EPI vaccination coverage. Additionally, Amref and other stakeholders should support us build health posts in five difficult-to-reach kebeles in Woreda. Consequently, this will help us increase immunization coverage.”

Similarly, HEWs also described NGO partners who were involved in supporting vaccination activities. One extension worker described this as follows:

“Amref, supported us on implementation of capacity building of voluntary communities Woreda level review meetings and the EPI Vaccination program.The WoredaHealth Office supported us in vaccinelogistics supply and transportation, but it is not enough if any partnersupported uswith a transportation vehicle with fuel; it would help us to enhance our vaccination coverage.”

Community engagement: According to the EPI focal people from different health facilities, they described the importance of community engagement as a new practice for improving vaccination programs.

“The community representatives should participate during the planning and implementation of immunization activities. For example, in deciding the outreach sites, targetidentification,and arrangement of the services.Therefore, their participation will help us toachievebetter vaccination coverage.”

3.7. Factors Associated with Full Immunization among Children

Mothers and caretakers who had received formal education were almost four times more likely to have vaccinated their children than those who had not received formal education [Adjusted Odds Ratio (AOR)=3.90; 95% CI: (1.53-9.98)].

The presence of mobile phones at home was found to be significantly associated with the vaccination status of children, as the odds of being vaccinated were three times greater among study participants who owned mobile phones than among study participants who had no mobile phones at home [AOR=2.99; 95% CI: (1.33-6.76)].

The odds of being vaccinated were 2.39 times greater among mothers who had attended at least one ANC visit than among mothers who had not attended ANC follow-up [AOR=2.39; 95% CI: (1.14-5.01)].

Mothers who gave birth at a health facility were 5.79 times more likely to vaccinate their children than mothers who gave birth at home [AOR=5.79; 95% CI: (2.77-12.12)] (Table 8).

4. Discussion

This study assessed vaccination coverage and associated factors among children aged 12 to 23 months in three woredas in the Afar region of Ethiopia. The full immunization status of the children was assessed using vaccination cards and the mothers’ recall method.

The proportion of full vaccination was found to be 25.1% among children aged 12 to 23 months. The immunization coverage across the three woredas differed, which is related to the difference in study participants or respondents, as there was a greater proportion of urban residents in the Elidar and Gereni woredas. This finding is greater than that of the Afar regional state being fully vaccinated according to the Mini-EDHS report of 2019 and another study conducted in the Amibara District of Africa in 2013 [10,11,16]. Similarly, based on systematic and meta-analysis reports of vaccination coverage studies in Ethiopia, this percentage is greater than the proportion of full vaccination in the Afar region, which was 21% (95% CI: 18, 24%)] [17]. This difference could be due to the study setting of the EDHS survey and the improvement of vaccination over time, as there is a time difference.

However, this finding is lower than that of other vaccination coverage reports from other parts of the country. A systematic meta-analysis of vaccination coverage studies in Ethiopia was performed. The overall prevalence of full vaccination coverage among children in Ethiopia was 60% (95% CI: 51, 69%) [17]. Moreover, this finding is less than that of studies conducted in other parts of the country. This could be related to the known weather conditions of the region and the national security issues that could also contribute to this low coverage status. The qualitative findings indicated that distance to health facilities is the main barrier to vaccination services throughout the region. The greatest problem for desert or Berhama areas such as the Afar region is the lack of health facilities, which makes vaccination services inaccessible and creates problems in the supply chain of vaccines. Moreover, pastoralists’ mobile lifestyle is also one possible reason for low vaccination coverage. This indicates the need for integrated mobile and outreach immunization services for hard-to-reach areas, especially pastoral and semi pastoral regions.

The proportion of MCV1 among children aged 12-23 months was 54.4%. The proportion of second-dose measles among children aged 15-23 months was 44.2%. This finding is lower than the WHO-recommended proportion of patients receiving second-dose measles.

Mothers’ and caretakers’ educational status was found to be significantly associated with full vaccination status, as mothers and caretakers who had attended formal education were almost four times more likely to vaccinate their children than those who did not attend formal education. This finding was consistent with other studies performed in other areas of the country [7,11,18]. The findings suggest that complete immunization was more common in children whose mothers were educated, partly because maternal education leads to the acquisition of literacy skills that can be applied to knowledge of vaccination and child protection and better health-seeking behaviours, which then improves immunization uptake for their children.

The odds of being vaccinated were three times greater among study participants who owned mobile phones. This could be an important finding, as making contact with mothers for appointments can be facilitated through mobile phones. Multiple studies have indicated that mobile health (mHealth) interventions can improve access to MCH services. A meta-analysis in developing countries indicated that mobile phone reminders were beneficial [15,19]

The odds of being vaccinated were 2.39 times greater among mothers who had attended at least one ANC visit than among mothers who had not attended ANC follow-up. This finding is in agreement with other studies conducted in Ethiopia [16,19,20]. This could be related to the counseling given at health facilities during ANC follow-up, which may bring about the desired behavioural change toward vaccines. ANC follow-up provides an opportunity to promote health care utilization, including institutional delivery, PNC, immunization and family planning. According to a propensity score matching analysis on strategies to improve child immunization via ANC, antenatal clinics are the conventional platforms for educating pregnant women on the benefits of child immunization [21].

Mothers who gave birth at a health facility were more likely to vaccinate their children than mothers who gave birth at home. This finding is in line with findings from previous studies showing that institutional birth increased the chances of children being fully vaccinated [16,20]. Mothers may be advised and receive education to use postnatal care and vaccination services during institutional birth. Women who give birth in health facilities may also be more inclined to use preventive services, such as infant immunization. The greater likelihood of receiving a complete immunization may also be attributable to the prompt administration of the BCG vaccine following childbirth and vaccination advice received at a medical facility.

5. Conclusions and Recommendation

The overall proportion of full immunization was 25.1%, which is lower than that of the UNICEF Strategic Plan, 2018-2021, which calls for at least 90% immunization coverage at the national level and at least 80% immunization coverage at the district level. Based on vaccination card observations, the dropout rate from Pentavalet-1 to Pentavalent-3 was found to be 2.9%. Having formal education, owning mobile phones, attending an ANC visit and birthing in a health facility were positively and significantly associated with full immunization.

The Ethiopian government should focus on improving the level of education among women, as education can contribute to greater vaccination coverage. Additionally, the government and other stakeholders should engage in improving access to and promoting the use of maternal healthcare services such as antenatal clinics and birthing health facilities using different strategies to increase immunization coverage. Generally, HCWs should integrate child vaccination services with other health services, such as maternal health care services. Therefore, the government, NGOs, and other stakeholders should strengthen the expansion of immunization services by increasing and sustaining a focus on outreach programs to hard-to-reach areas of the country. Additionally, our qualitative findings indicate the need for community participation and engagement as well as collaboration between the governmental service delivery system and NGOs in alleviating existing vaccination-related problems such as the construction of health facilities and making services accessible through the mobile health approach. Moreover, the study also indicated that work must be done in relation to motivating health workers, including HEWs.