Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Urinary Tract Infections in Kidney Transplant Patients Admitted to Hospital: A Real-Life Experience

Version 1 : Received: 21 May 2024 / Approved: 21 May 2024 / Online: 23 May 2024 (12:04:51 CEST)

How to cite: Pinchera, B.; Schettino, E.; D'Agostino, A.; Trucillo, E.; Cuccurullo, F.; Salemi, F.; Piccione, A.; Carrano, R.; Gentile, I. Urinary Tract Infections in Kidney Transplant Patients Admitted to Hospital: A Real-Life Experience. Preprints 2024, 2024051400. https://doi.org/10.20944/preprints202405.1400.v1 Pinchera, B.; Schettino, E.; D'Agostino, A.; Trucillo, E.; Cuccurullo, F.; Salemi, F.; Piccione, A.; Carrano, R.; Gentile, I. Urinary Tract Infections in Kidney Transplant Patients Admitted to Hospital: A Real-Life Experience. Preprints 2024, 2024051400. https://doi.org/10.20944/preprints202405.1400.v1

Abstract

Urinary tract infections in kidney transplant patients are a real challenge. We conducted a retrospective observational study, enrolling all kidney transplant patients hospitalized for urinary tract infection (UTI), with the objective to evaluate the epidemiology, clinical sta-tus, therapeutic management, and clinical outcome of kidney transplant patients hospi-talized for urinary tract infection in a university hospital. From our real-life experience, infection with multidrug-resistant germs was confirmed as a risk factor for the severe evolution of the infection and at the same time the re-evaluation of immunosuppressive therapy could be an important therapeutic strategy in the course of infection. Prompt ini-tiation of empiric antibiotic therapy upon initiation of microbiological investigations could potentially reduce the risk of severe infection progression.

Keywords

urinary tract infections; kidney transplant; MDR; SOT; empiric therapy

Subject

Medicine and Pharmacology, Transplantation

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