PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
The Effectiveness of Pattern Scanning Laser Trabeculoplasty as an Additional Treatment for the Patients of Open-Angle Glaucoma Receiving Full Ocular Hypotensive Medications.
Version 1
: Received: 28 April 2024 / Approved: 29 April 2024 / Online: 29 April 2024 (15:25:14 CEST)
How to cite:
Ueno, Y.; Haruna, Y.; Tomita, M.; Sakai, A.; Ogawa, S.; Honda, S. The Effectiveness of Pattern Scanning Laser Trabeculoplasty as an Additional Treatment for the Patients of Open-Angle Glaucoma Receiving Full Ocular Hypotensive Medications.. Preprints2024, 2024041932. https://doi.org/10.20944/preprints202404.1932.v1
Ueno, Y.; Haruna, Y.; Tomita, M.; Sakai, A.; Ogawa, S.; Honda, S. The Effectiveness of Pattern Scanning Laser Trabeculoplasty as an Additional Treatment for the Patients of Open-Angle Glaucoma Receiving Full Ocular Hypotensive Medications.. Preprints 2024, 2024041932. https://doi.org/10.20944/preprints202404.1932.v1
Ueno, Y.; Haruna, Y.; Tomita, M.; Sakai, A.; Ogawa, S.; Honda, S. The Effectiveness of Pattern Scanning Laser Trabeculoplasty as an Additional Treatment for the Patients of Open-Angle Glaucoma Receiving Full Ocular Hypotensive Medications.. Preprints2024, 2024041932. https://doi.org/10.20944/preprints202404.1932.v1
APA Style
Ueno, Y., Haruna, Y., Tomita, M., Sakai, A., Ogawa, S., & Honda, S. (2024). The Effectiveness of Pattern Scanning Laser Trabeculoplasty as an Additional Treatment for the Patients of Open-Angle Glaucoma Receiving Full Ocular Hypotensive Medications.. Preprints. https://doi.org/10.20944/preprints202404.1932.v1
Chicago/Turabian Style
Ueno, Y., Shogo Ogawa and Shigeru Honda. 2024 "The Effectiveness of Pattern Scanning Laser Trabeculoplasty as an Additional Treatment for the Patients of Open-Angle Glaucoma Receiving Full Ocular Hypotensive Medications." Preprints. https://doi.org/10.20944/preprints202404.1932.v1
Abstract
Purpose: To examine the effectiveness of patterned laser trabeculoplasty (PSLT) as an additional treatment for patients of open-angle glaucoma (OAG) receiving maximized ocular hypotensive medications (OHM).
Methods: Forty eyes of 33 patients (average age 72.7±10.7 years) who had not previously undergone open glaucoma surgery or laser trabeculoplasty and were treated with maximized OHM between June 2018 and March 2022 were included. A 360-degree PSLT was conducted and postoperative intraocular pressure (IOP) and survival curves at 1, 3, 6, 9, and 12 months were evaluated.
Results: According to the Kaplan-Meier survival analysis, the average survival time was 8.1 months with death defined as postoperative IOP reduction of less than 10% or requiring additional treatment. The average survival time was 4.9 months with death defined as postoperative IOP reduction of less than 20% or requiring additional treatment. In the 31 eyes which received no additional treatment after PSLT, the mean preoperative IOP was 18.5±3.9 mmHg, which reduced to 15.3±4.1 mmHg (p=1.62 x 10-6)), 15.5±3.4 mmHg (p=1.51 x 10-5), 15.7±4.0 mmHg (p=1.75 x 10-5), 14.7±4.38 (p=2.89 x 10-6), and 15.0±4.0 mmHg (p=5.74 x 10-9) at 1, 3, 6, 9 and 12 months after PSLT, respectively. The IOP reduction rate one year after PSLT was 18.7%. Thirteen of the 31 eyes (42%) achieved a 20% reduction in IOP compared to the baseline.
Conclusion: Adjunctive treatment with PSLT in OAG patients receiving maximized OHM may be effective over 12-months of follow-up.
Keywords
glaucoma; pattern scanning laser trabeculoplasty; full ocular hypotensive medications
Subject
Medicine and Pharmacology, Ophthalmology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
