Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

The Predictive Value of RDW-CV in Pregnant Patients with Treated Thrombophilia Who Delivered via Cesarean Section at Term

Catalina Filip
ORCID logo ,
Roxana Covali
* ORCID logo ,
Demetra Socolov
,
Ingrid Andrada Vasilache
ORCID logo ,
Alexandru Carauleanu
,
Mona Akad
* ,
Ioana Sadyie Scripcariu
,
Tudor Butureanu
ORCID logo ,
Gabriela Dumachita-Sargu
,
Lucian Vasile Boiculese
,
Alina Melinte
,
Razvan Socolov
ORCID logo
Version 1 : Received: 26 April 2024 / Approved: 28 April 2024 / Online: 28 April 2024 (08:31:01 CEST)

How to cite: Filip, C.; Covali, R.; Socolov, D.; Vasilache, I.A.; Carauleanu, A.; Akad, M.; Scripcariu, I.S.; Butureanu, T.; Dumachita-Sargu, G.; Boiculese, L.V.; Melinte, A.; Socolov, R. The Predictive Value of RDW-CV in Pregnant Patients with Treated Thrombophilia Who Delivered via Cesarean Section at Term. Preprints 2024, 2024041836. https://doi.org/10.20944/preprints202404.1836.v1 Filip, C.; Covali, R.; Socolov, D.; Vasilache, I.A.; Carauleanu, A.; Akad, M.; Scripcariu, I.S.; Butureanu, T.; Dumachita-Sargu, G.; Boiculese, L.V.; Melinte, A.; Socolov, R. The Predictive Value of RDW-CV in Pregnant Patients with Treated Thrombophilia Who Delivered via Cesarean Section at Term. Preprints 2024, 2024041836. https://doi.org/10.20944/preprints202404.1836.v1

Abstract

(1) Background: The RDW-CV has predictive value in many pregnancy-related conditions. Re-search question: Can the RDW-CV be utilized predictively in pregnant patients with thrombo-philia? Aim of the study: To carry out a detailed analysis of the RDW-CV in pregnant patients with treated thrombophilia as compared with pregnant patients without thrombophilia who de-livered via cesarean section at term. (2) Methods: We studied 160 pregnant patients, including 80 pregnant patients with treated thrombophilia in the study group, and another 80 patients of a similar age and parity. The patients were referred to our hospital for delivery at term by means of a cesarean section between 1/10/2017 and 1/12/2021. Every patient received a sonogram during the first 1–2 days after the cesarean section, and their uterine evaluation was interpreted using the PUUS (Postpartum Uterine Ultrasonographic Scale). (3) Results: Our PUUS≥1 pregnant and postpartum patients with treated thrombophilia were the only group with an RDW-CV value over 14. No deep vein thrombosis was observed during hospitalization, showing that the antico-agulant treatment was necessary and effective. An RDW-CV of 14.5 was the highest value in the Rh-negative group of pregnant patients with treated thrombophilia. An RDW-CV of 14.48 was the highest level in the Rh-negative postpartum patients with treated thrombophilia. (4) Conclu-sion: An RDW-CV of ≥14 can predict uterine hematometra (PUUS≥1). The RDW-CV values were higher in Rh-negative patients.

Keywords

RDW-CV; thrombophilia; pregnancy; cesarean section; Rh-factor; postpartum; uterine; ultrasonography; scale

Subject

Medicine and Pharmacology, Obstetrics and Gynaecology

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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