Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Issues Surrounding the Stability of Hypochlorous Acid as a Disinfectant

Version 1 : Received: 15 April 2024 / Approved: 15 April 2024 / Online: 15 April 2024 (10:54:11 CEST)

How to cite: Alshahrani, F.; Elgujja, A.; Elgujja, A.; Alamoudi, A.; Asiri, S.; Alzaid, I. Issues Surrounding the Stability of Hypochlorous Acid as a Disinfectant. Preprints 2024, 2024040954. https://doi.org/10.20944/preprints202404.0954.v1 Alshahrani, F.; Elgujja, A.; Elgujja, A.; Alamoudi, A.; Asiri, S.; Alzaid, I. Issues Surrounding the Stability of Hypochlorous Acid as a Disinfectant. Preprints 2024, 2024040954. https://doi.org/10.20944/preprints202404.0954.v1

Abstract

Abstract Background: Hypochlorous acid (HA) is a potent disinfectant with broad-spectrum antimicrobial activity against bacteria, fungi, and viruses. Aim: This study aimed to investigate the factors that influence the stability of hypochlorous acid (HOCl) and their impact on its disinfectant properties Methods: This study explored the stability of hypochlorous acid, emphasizing factors that affect its disinfectant efficiency, such as pH level, temperature, and the presence of organic materials. Findings: Our investigation revealed that HOCl is the most stable and effective disinfectant under weakly acidic conditions, where the undissociated form of hypochlorous acid is predominant. Although it is stable under various conditions, its efficacy is compromised by the presence of heavy metals, organic matter, and UV radiation. Conclusions: This comprehensive analysis concludes that, while hypochlorous acid is a highly effective disinfectant, understanding and maintaining the optimal conditions for its stability is crucial for maximizing its disinfection potential. Implications: The findings can be used to formulate new guidelines and regulations to guide the proper formulation, storage, and use of stable HOCL as disinfectants.

Keywords

hypochlorous acid; HOCL; disinfectant stability; surface disinfectants; electrochemical activation; electrolysis

Subject

Public Health and Healthcare, Public, Environmental and Occupational Health

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