Version 1
: Received: 10 April 2024 / Approved: 11 April 2024 / Online: 11 April 2024 (07:33:36 CEST)
How to cite:
Meng, Q.; Su, C. The Impact of Physical Exercise on Oxidative and Nitrosative Stress: Balancing the Benefits and Risks. Preprints2024, 2024040770. https://doi.org/10.20944/preprints202404.0770.v1
Meng, Q.; Su, C. The Impact of Physical Exercise on Oxidative and Nitrosative Stress: Balancing the Benefits and Risks. Preprints 2024, 2024040770. https://doi.org/10.20944/preprints202404.0770.v1
Meng, Q.; Su, C. The Impact of Physical Exercise on Oxidative and Nitrosative Stress: Balancing the Benefits and Risks. Preprints2024, 2024040770. https://doi.org/10.20944/preprints202404.0770.v1
APA Style
Meng, Q., & Su, C. (2024). The Impact of Physical Exercise on Oxidative and Nitrosative Stress: Balancing the Benefits and Risks. Preprints. https://doi.org/10.20944/preprints202404.0770.v1
Chicago/Turabian Style
Meng, Q. and Chun-Hsien Su. 2024 "The Impact of Physical Exercise on Oxidative and Nitrosative Stress: Balancing the Benefits and Risks" Preprints. https://doi.org/10.20944/preprints202404.0770.v1
Abstract
This general review assesses the impact of physical exercise on oxidative and nitrosative stress and the counteractive role of antioxidants, drawing from a systematic literature search up to March 2024 in databases like PubMed and Web of Science. The review highlights studies on the effect of exercise on the production of reactive oxygen species (ROS) and reactive nitrogen species (RNS) and antioxidant responses in both human and animal models based on rigorous inclusion and exclusion criteria. Due to the variety of exercise types and participants' characteristics, a narrative synthesis approach was adopted. The findings indicate that moderate exercise boosts antioxidant defenses, known as hormesis, whereas excessive physical activity may increase oxidative and nitrosative damage. The review also explores the complex effects of antioxidant supplementation, revealing that while natural dietary antioxidants support health, high-dose supplements could potentially hinder positive adaptations to exercise. Recommendations for athletes and the general active population highlight the importance of balancing exercise and dietary intake to optimize health benefits. The review concludes with a call for more detailed research on tailored exercise and nutrition plans to dissect these intricate relationships further.
Public Health and Healthcare, Physical Therapy, Sports Therapy and Rehabilitation
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
