Version 1
: Received: 3 April 2024 / Approved: 3 April 2024 / Online: 4 April 2024 (09:16:27 CEST)
How to cite:
MOISII, P.; JARI, I.; URSU, A.M.; NAUM, A.G. The Relationship between Job Strain and Ischemic Heart Disease, Mediated by Endothelial Dysfunction Markers and Imaging. Preprints2024, 2024040333. https://doi.org/10.20944/preprints202404.0333.v1
MOISII, P.; JARI, I.; URSU, A.M.; NAUM, A.G. The Relationship between Job Strain and Ischemic Heart Disease, Mediated by Endothelial Dysfunction Markers and Imaging. Preprints 2024, 2024040333. https://doi.org/10.20944/preprints202404.0333.v1
MOISII, P.; JARI, I.; URSU, A.M.; NAUM, A.G. The Relationship between Job Strain and Ischemic Heart Disease, Mediated by Endothelial Dysfunction Markers and Imaging. Preprints2024, 2024040333. https://doi.org/10.20944/preprints202404.0333.v1
APA Style
MOISII, P., JARI, I., URSU, A.M., & NAUM, A.G. (2024). The Relationship between Job Strain and Ischemic Heart Disease, Mediated by Endothelial Dysfunction Markers and Imaging. Preprints. https://doi.org/10.20944/preprints202404.0333.v1
Chicago/Turabian Style
MOISII, P., ANDRA MARA URSU and ALEXANDRU GRATIAN NAUM. 2024 "The Relationship between Job Strain and Ischemic Heart Disease, Mediated by Endothelial Dysfunction Markers and Imaging" Preprints. https://doi.org/10.20944/preprints202404.0333.v1
Abstract
Background and Objectives: High job strain is worsening the outcome in coronary artery disease, CAD. Severe dissatisfaction on workplace, imbalance between high demands , and low rewards, are affecting the quality of life, and diminishing the duration of life, especially in CAD patients. Our study included two samples : CAD patients (experimental group), and without CAD patients, but with traditional risk factors (control group). The main objective of the study was the role played by high sensitivity C reactive protein, hs CRP, and microalbuminuria, as mediators of job strain and CAD relationship. Secondary objectives were the following: identification of the most vulnerable patients( with significant job strain) and intervention towards this category, for cardiovascular events prevention (primary or secondary). Materials and Methods: The utilized methods were the following : clinical exam; electrocardiogram; echocardiogram; non contrast enhanced computed chest tomography; laboratory findings ( lipid profile, glycemia, hs CRP, microalbuminuria); type D scale, DS 14; depression questionnaire, PHQ-9; and satisfaction with work scale, SWWS. Results: The highest values for hs CRP and microalbuminuria were noticed in patients with the lowest Likert score, for both samples CAD, and without CAD patients. The highest job strain was noticed in females. More than half of CAD patients ,with low Likert scores, revealed myocardial infarction. Conclusions: Microalbuminuria and hs CRP were statistical significant in the study as intercessors, in job strain and CAD relationship. The most vulnerable patients for vascular events were females, in both groups : CAD and “CAD waiting desk”. In CAD sample, the vascular vulnerability was also increased by high job strain.
Keywords
coronary artery disease; cardiovascular risk; job strain; high sensitivity C reactive protein; microalbuminuria
Subject
Medicine and Pharmacology, Cardiac and Cardiovascular Systems
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
