Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Pre-pandemic Predictivity of Anxious-Depressive Symptoms in Post-surgical Traumatic Distress in Hysterectomy for Benign Disease and COVID-19 Outbreak: A Case-Control Study

Marta Ielmini
,
Jvan Casarin
,
Camilla Callegari
ORCID logo ,
Alessandro Bellini
,
Manuela Giada Favata
ORCID logo ,
Anna Giudici
,
Fabio Ghezzi
ORCID logo ,
Antonella Cromi
,
Ivano Caselli
* ORCID logo
Version 1 : Received: 2 April 2024 / Approved: 3 April 2024 / Online: 3 April 2024 (10:35:06 CEST)

How to cite: Ielmini, M.; Casarin, J.; Callegari, C.; Bellini, A.; Favata, M.G.; Giudici, A.; Ghezzi, F.; Cromi, A.; Caselli, I. Pre-pandemic Predictivity of Anxious-Depressive Symptoms in Post-surgical Traumatic Distress in Hysterectomy for Benign Disease and COVID-19 Outbreak: A Case-Control Study. Preprints 2024, 2024040274. https://doi.org/10.20944/preprints202404.0274.v1 Ielmini, M.; Casarin, J.; Callegari, C.; Bellini, A.; Favata, M.G.; Giudici, A.; Ghezzi, F.; Cromi, A.; Caselli, I. Pre-pandemic Predictivity of Anxious-Depressive Symptoms in Post-surgical Traumatic Distress in Hysterectomy for Benign Disease and COVID-19 Outbreak: A Case-Control Study. Preprints 2024, 2024040274. https://doi.org/10.20944/preprints202404.0274.v1

Abstract

The Sars-Cov-2 pandemic led to several needed containing measures that conditioned the onset of depressive, anxiety and post-traumatic stress symptoms in population. These symptoms, espe-cially if not diagnosed and treated, can also occur in patients undergoing surgery with high im-pact on people’s lives, like hysterectomy. To evaluate the post-surgical distress and anx-ious-depressive symptoms following hysterectomy for benign disease focusing on the impact of COVID-19 pandemic. The prospective observational cohort study included patients undergoing hysterectomy for benign disease. Psychologic evaluation through social-demographic question-naires was obtained before surgery (T1), postoperatively (T2), and 3 months after surgery (T3). The HADS (Hospital Anxiety and Depression Scale) was used to evaluate anxious-depressive symptoms and the PCL-5 (Post-traumatic Stress Disorder Checklist for DSM-5) compared the on-set of post-surgical distress and anxiety and depressive symptoms. The pre-COVID-19 pan-demic period was compared to the post-COVID-19 pandemic phase. Patients treated after COVID-19 pandemic showed higher depressive symptoms rate compared to those treated before (p-value=0.02); conversely, pre-COVID-19 patients were more prone to develop a PTSD (p-value=0.04). A significative association between the occurrence PTSD and anxiety-depressive symptoms registered at T2 a (p-value=0.007) and T3 (p-value

Keywords

post-traumatic stress disorder; post-surgical traumatic distress; anxiety; depression; hysterecto-my; COVID-19

Subject

Medicine and Pharmacology, Psychiatry and Mental Health

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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