Prostate Cancer Lung Metastasis: Clinical Insights and Therapeutic Strategies

How to cite: Mahmoud, A.M.; Moustafa, A.; Day, C.; Ahmed, M.E.; Zeina, W.; Marzouk, U.M.; Basourakos, S.; Haloi, R.; Mahon, M.; Muniz, M.; Childs, D.S.; Orme, J.J.; Riaz, I.B.; Kendi, A.T.; Stish, B.J.; Davis, B.J.; Kwon, E.D.; Andrews, J.R. Prostate Cancer Lung Metastasis: Clinical Insights and Therapeutic Strategies. Preprints 2024, 2024040193. https://doi.org/10.20944/preprints202404.0193.v1 Mahmoud, A.M.; Moustafa, A.; Day, C.; Ahmed, M.E.; Zeina, W.; Marzouk, U.M.; Basourakos, S.; Haloi, R.; Mahon, M.; Muniz, M.; Childs, D.S.; Orme, J.J.; Riaz, I.B.; Kendi, A.T.; Stish, B.J.; Davis, B.J.; Kwon, E.D.; Andrews, J.R. Prostate Cancer Lung Metastasis: Clinical Insights and Therapeutic Strategies. Preprints 2024, 2024040193. https://doi.org/10.20944/preprints202404.0193.v1

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MDPI and ACS Style

Mahmoud, A.M.; Moustafa, A.; Day, C.; Ahmed, M.E.; Zeina, W.; Marzouk, U.M.; Basourakos, S.; Haloi, R.; Mahon, M.; Muniz, M.; Childs, D.S.; Orme, J.J.; Riaz, I.B.; Kendi, A.T.; Stish, B.J.; Davis, B.J.; Kwon, E.D.; Andrews, J.R. Prostate Cancer Lung Metastasis: Clinical Insights and Therapeutic Strategies. Preprints 2024, 2024040193. https://doi.org/10.20944/preprints202404.0193.v1

APA Style

Mahmoud, A.M., Moustafa, A., Day, C., Ahmed, M.E., Zeina, W., Marzouk, U.M., Basourakos, S., Haloi, R., Mahon, M., Muniz, M., Childs, D.S., Orme, J.J., Riaz, I.B., Kendi, A.T., Stish, B.J., Davis, B.J., Kwon, E.D., & Andrews, J.R. (2024). Prostate Cancer Lung Metastasis: Clinical Insights and Therapeutic Strategies. Preprints. https://doi.org/10.20944/preprints202404.0193.v1

Chicago/Turabian Style

Mahmoud, A.M., Eugene D. Kwon and Jack R. Andrews. 2024 "Prostate Cancer Lung Metastasis: Clinical Insights and Therapeutic Strategies" Preprints. https://doi.org/10.20944/preprints202404.0193.v1

Abstract

Prostate cancer lung metastasis represents a clinical conundrum due to their implication of advanced disease progression and the complexities they introduce in treatment planning. As the disease progresses to distant sites such as the lung, the clinical management becomes increasingly intricate, requiring tailored therapeutic strategies to address the unique characteristics of metastatic lesions. This review seeks to synthesize the current state of knowledge surrounding prostate cancer metastasis to the lung, shedding light on the diverse array of clinical presentations encountered, ranging from subtle radiological findings to overt symptomatic manifestations. By examining the diagnostic modalities utilized in identifying this metastasis, including advanced imaging techniques and histopathological analyses, the review aims to provide insights into the diagnostic landscape and the challenges associated with accurately characterizing lung metastatic lesions in prostate cancer patients. Moreover, the review delves into the nuances of therapeutic interventions employed in managing prostate cancer lung metastasis, encompassing systemic treatments such as hormonal therapies and chemotherapy, as well as metastasis-directed therapies including surgery and radiotherapy.

Keywords

Prostate Cancer; Lung Metastasis; Systemic Therapy; Metastasis-Directed therapy

Subject

Medicine and Pharmacology, Oncology and Oncogenics

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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