PreprintArticleVersion 1Preserved in Portico This version is not peer-reviewed
Relationship between Glucose 6-Phosphate Dehydrogenase and Pyruvate Kinase Deficiency with New Generation Inflammation Biomarkers of in Term Newborns with Prolonged Neonatal Jaundice
Version 1
: Received: 26 March 2024 / Approved: 27 March 2024 / Online: 27 March 2024 (08:12:05 CET)
How to cite:
Okuyan, O.; Elgormus, Y.; Dumur, S.; Uzun, H. Relationship between Glucose 6-Phosphate Dehydrogenase and Pyruvate Kinase Deficiency with New Generation Inflammation Biomarkers of in Term Newborns with Prolonged Neonatal Jaundice. Preprints2024, 2024031649. https://doi.org/10.20944/preprints202403.1649.v1
Okuyan, O.; Elgormus, Y.; Dumur, S.; Uzun, H. Relationship between Glucose 6-Phosphate Dehydrogenase and Pyruvate Kinase Deficiency with New Generation Inflammation Biomarkers of in Term Newborns with Prolonged Neonatal Jaundice. Preprints 2024, 2024031649. https://doi.org/10.20944/preprints202403.1649.v1
Okuyan, O.; Elgormus, Y.; Dumur, S.; Uzun, H. Relationship between Glucose 6-Phosphate Dehydrogenase and Pyruvate Kinase Deficiency with New Generation Inflammation Biomarkers of in Term Newborns with Prolonged Neonatal Jaundice. Preprints2024, 2024031649. https://doi.org/10.20944/preprints202403.1649.v1
APA Style
Okuyan, O., Elgormus, Y., Dumur, S., & Uzun, H. (2024). Relationship between Glucose 6-Phosphate Dehydrogenase and Pyruvate Kinase Deficiency with New Generation Inflammation Biomarkers of in Term Newborns with Prolonged Neonatal Jaundice. Preprints. https://doi.org/10.20944/preprints202403.1649.v1
Chicago/Turabian Style
Okuyan, O., Seyma Dumur and Hafize Uzun. 2024 "Relationship between Glucose 6-Phosphate Dehydrogenase and Pyruvate Kinase Deficiency with New Generation Inflammation Biomarkers of in Term Newborns with Prolonged Neonatal Jaundice" Preprints. https://doi.org/10.20944/preprints202403.1649.v1
Abstract
Background: Glucose 6-phosphate dehydrogenase (G6PD) deficiency increases the risk of neonatal hyperbilirubinemia. The aim of the study is to evaluate the clinical findings of glucose 6 phosphate dehydrogenase (G6PD) and pyruvate kinase (PK) deficiency, to prevent further examinations for prolonged jaundice, and to contribute by regulating its treatment. At the same time, it is to determine whether systemic-immune-inflammation index (SII), neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) can be used in addition to conventional complete blood count (CBC) parameters in the diagnosis of neonatal prolonged jaundice. Methods: In full term neonates with hyperbilirubinemia who were admitted to Medicine Hospital between January 2019 and January 2024 with the complaint of jaundice, 167 infants with a serum bilirubin level above 5 mg/dL, whose jaundice persisted after the 10th day, were included in the study. Results: 63.5% of the patients were male and the mean age was 31±6 days. G6PD was negatively perfectly correlated with NLR (r: -1; p
Keywords
Prolonged jaundice, breast milk, glucose 6 phosphate dehydrogenase, pyruvate kinase, systemic-immune-inflammation index, neutrophil-to-lymphocyte ratio
Subject
Medicine and Pharmacology, Clinical Medicine
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
