Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Botulinum Toxin in Chronic Lateral Epicondylitis, from Tendon to Muscle Approach

Version 1 : Received: 22 March 2024 / Approved: 22 March 2024 / Online: 25 March 2024 (07:57:48 CET)

A peer-reviewed article of this Preprint also exists.

Poenaru, D.; Sandulescu, M.I.; Potcovaru, C.-G.; Cinteza, D. Botulinum Toxin in Chronic Lateral Epicondylitis, from Tendon to Muscle Approach—A Review. Life 2024, 14, 528. Poenaru, D.; Sandulescu, M.I.; Potcovaru, C.-G.; Cinteza, D. Botulinum Toxin in Chronic Lateral Epicondylitis, from Tendon to Muscle Approach—A Review. Life 2024, 14, 528.

Abstract

Background: Chronic lateral epicondylitis challenges the therapeutical approach; underlying mechanisms are incompletely understood; neuropathic pain and central and peripheral sensitization may explain the fact that botulinum toxin was found to play a role in pain and function management. Methods: We searched the literature for MeSH terms: lateral epicondylitis or synonyms and botulinum toxin. Results: We found 14 papers containing trials on botulinum toxin injection into the tendon or into the extensor muscles (particularly extensor carpi radialis brevis and extensor communis digitorum). We followed the administration pathways, doses, timing and side effects. Conclusion: With chronic course, the focus of the therapy shifts from the afflicted tendon to the inserting muscles, as muscle contracture may create a vicious loop to perpetuate and aggravate the disease. Doses, timing and side effects are discussed.

Keywords

botulinum toxin; lateral epicondylitis; intramuscular injection; intratendinous injection

Subject

Medicine and Pharmacology, Anesthesiology and Pain Medicine

Comments (0)

We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.

Leave a public comment
Send a private comment to the author(s)
* All users must log in before leaving a comment
Views 0
Downloads 0
Comments 0


×
Alerts
Notify me about updates to this article or when a peer-reviewed version is published.
We use cookies on our website to ensure you get the best experience.
Read more about our cookies here.