HORMONE EFFECTS ON PERFORMANCE
Hormones directly affect an individual psychologically which directly affects physical performance. They are the chemical regulators of the human body in which changes of their levels affect the neuronal networking and mechanisms of cognitive function. Depending on the level of the hormones in the body they can contribute to both positive and negative outcomes. Their critical function is to regulate and maintain bodily processes that include growth, emotions, and cognition. Hormonal effects on cognitive function are investigated through analyzing the source of localization to understand the neuronal network that is involved. Therefore, cognitive function does not rely on any specific area within the brain but it is instead determined by the neuronal network interactions [
12]. Cognitive function deficit can occur when there are compromises to language, attention, conceptual reasoning, memory and processing speed. Hormones are outside of an individual’s conscious control, therefore if there is level fluctuation the body will respond to compensate for the changes. It is very important to be conscious of keeping the body, as well as the mind healthy in order to continuously perform at the highest potential especially in athletics.
There are numerous different hormones that deal with athletic performance, such as dopamine which is involved in motivational control. The motivation control deciphers good from bad and is able to choose actions to gain the good things and avoid the bad things [
13]. The cerebral cortex houses the major sources of dopamine. The subcortical areas contain the dopamine releasing neurons of the ventral midbrain which are located in
substantia nigra pars compacta and
ventral tegmental area. The neurons have two modes of dopamine differentiated into the “tonic” and “phasic”. The tonic mode of dopamine neurons maintains a steady baseline level of dopamine in downstream neural structures that is vital for enabling the normal functions of neural circuits [
13]. The phasic mode of dopamine neurons sharply increase or decrease their firing rates for 100-500 ms, directly causing greater changes in dopamine concentrations in downstream structures lasting for several seconds [
13]. The responses to phasic dopamine responses are triggered by different types of rewards and reward-related sensory cues. The phasic response purpose is to fulfill dopamine roles in motivational control, including its roles as a teaching signal that underlies reinforcement learning and as an incentive signal that promotes immediate reward seeking [
13]. The two types of dopamine neurons are further divided into differences in their effect on motivation. One type codes for motivation value, excited by rewarding events and inhibited by aversive events. The neurons encoding for motivational value support brain systems for seeking goals, evaluating outcomes, and value learning. The second type codes for motivational salience, excited by both rewarding and aversive effects. Both types of motivational value and motivational salience transmit an alerting signal, triggered by unexpected sensory cues of high potential importance. The transmission of these forms of dopamine is essential in creating a state of motivation in order to seek rewards and establishing memories of cue-reward associations. The release of dopamine is not necessary for all forms of reward learning. Additionally, dopamine release may not be enjoyed in the sense of causing pleasure, but it is crucial for causing goals to become wanted through the sense of wanting to achieve actions.
There has been recent research that dopamine will influence how the brain evaluates if a mental task is worth the effort that it takes [
14]. This is due to dopamine supporting reinforcement learning through adjusting the strength of synaptic connections between neurons. Dopamine controlling synaptic plasticity was determined through a modified Hebbian rule that states as “neurons that fire together wire together, as long as they get a burst of dopamine.” This is explained by: if cell A activates cell B, and cell B causes a behavioral action that results in a reward, then dopamine would be released and the A to B connection would be reinforced [
13]. This phenomenon is the reason an individual is able to learn the optimal choice of actions to gain rewards, given sufficient trial-and-error experience. Therefore, the levels of dopamine within an individual are incredibly important to everyday activities. It is important that individuals are engaging in such activities to keep positive feelings and emotions flowing. It has been concluded from a study that individuals with higher levels of dopamine in the caudate nucleus of the brain were more likely to focus on the benefits and choose the difficult mental tasks. The individuals with lower dopamine levels were more sensitive to the perceived cost, or task difficulty [
14]. This study was followed up by another study to further research the decision making process influenced by different levels of dopamine. The researcher’s observed the participants’ eye movement as they reviewed information about task difficulty and the amount of money they would receive. The participant’s gaze patterns suggested that dopamine didn’t alter their attention to benefits vs costs, however it increased how much weight people gave to the benefits once they were looking at them [
14]. There is confirmed evidence that dopamine affects the motivational aspects of performance. It also affects the amount of focus put onto a task. In athletics focus and attention is important in order to perform to their best ability. If there are outside factors that are affecting an athlete’s dopamine levels, it can unknowingly affect their performance on the field as well as their work ethic to work harder. Hormone imbalances can prompt mental health issues, or beginning to struggle with mental health can alter hormonal levels. Therefore, athletes struggling with mental health may experience a decrease in performance without truly understanding why. The physiological processes become disrupted through hormone imbalance, especially when struggling with mental health and dopamine levels decrease. Athletes that once were very passionate about their sport may lose their motivation to put any work in, especially if dopamine levels become low or begin to fluctuate.
Cortisol is another hormone that is important in regulating vital functions including metabolism and immune function. The human body produces cortisol every morning as a part of the daily hormone cycle [
15]. This hormone is normally good for the body as it can help an individual focus and stay energized through a short period of time, due to its essential function in the body’s fight or flight response. When the body is exposed to a stressful situation, putting the body into fight or flight mode, more cortisol will be produced and released. However, if the stressful situation or state lingers for long periods of time high levels of cortisol will be maintained and the body goes into overdrive. The prolonged state of stress can either be mental or physical, the elevated cortisol levels will have the same effect on the body. If an athlete does not allow time for sufficient recovery and rest, they can suffer numerous consequences which include muscle soreness, more injuries, slower injury recovery, energy loss and lack of focus [
15]. When cortisol levels are elevated, muscles are stagnant in a tense state because they are in a constant state of “readiness” due to the body not being able to recognize if a threat has passed. High cortisol levels are also associated with reduced blood flow and a build-up of lactic acid causing increased muscle soreness, due to blood not reaching the muscles as rapidly and being surrounded by lactic acid. High cortisol levels decrease the body’s white blood platelet cells which decreases the rate of recovery of muscles. In addition, high cortisol decreases the bone formation process. High stress levels have been associated with lower bone mineral density and weaker bones [
15]. Since high cortisol levels cause decreased performance training it can cause athletes to overwork themselves which causes increased fatigue and depression. This is due to severely high levels of cortisol causing insomnia since cortisol regulates the sleep-wake cycle. The sleep-wake cycle is regulated by cortisol through levels rising in the morning to wake up, and decreasing at night to fall and stay asleep. Therefore, with high levels of cortisol disrupting an individual’s ability to sleep, it can lead to additional factors such as fatigue, mood swings and lack of focus.
There has been research performed and analyzed about cortisol levels and athletic performance that has led to the development of the “overtraining syndrome”. If an athlete is training excessively, without proper rest and recovery, cortisol levels will be chronically elevated. The chronically elevated cortisol levels can manifest into symptoms of uncontrolled tissue inflammation and suppressed immunity [
16]. However, some athletes may not immediately be symptomatic with manifests into poor performance in their area of sport. The overtraining syndrome is defined as an athlete overtraining but consistently unable to perform to their best ability because their body is overwhelmed by high levels of cortisol produced from overtraining. The overall research of the impact of cortisol on individual athletic performance needs to be more thoroughly studied, however there is enough evidence to show a negative correlation of athletic performance with increased levels of cortisol. There is evidence that cortisol concentrations were found to be positively correlated to speed, power, and strength in professional rugby union players, but in contrast another study on rugby players found values to be negatively correlated with the coaches’ evaluation of player performance [
17]. Normal cortisol levels are essential to athletic performance, however once they become too elevated it can negatively impact performance. If the athlete is not recognizing performance differences, coaches and staff will be able to pick up on the decrease in performance. Coaches and staff may blindly assume that the athlete is just not training themselves to their full potential or pushing themselves enough, however there is a deeper psychological function occurring.
Norepinephrine is a hormone that has vital functions in the fight or flight response. It is a neuromodulator that regulates the activity of neuronal and non-neuronal cells in multiple ways [
18]. Norepinephrine also participates in the rapid modulation of cortical circuits and cellular energy metabolism. On a slower time scale it participates in neuroplasticity and inflammation. The norepinephrine system displays synthesization through further hydroxylation of dopamine. In the central nervous system, norepinephrine is released by the noradrenergic neurons which are present in the locus coeruleus [
19]. The axons released by the noradrenergic neurons innervate the cerebral cortex, subcortical areas, cerebellum and brainstem. Norepinephrine, alongside epinephrine, are considered stress hormones that are responsible for many adaptations both at rest and during exercise in individuals [
20]. Exercise in general has been proven to enhance neuronal adaptation against harmful stimuli associated with stress. There is a productive mechanism of exercise against stress that has been attributed to the expression of galanin in locus coeruleus, where norepinephrine functions. Galanin hyperpolarizes noradrenergic neurons and inhibits locus coeruleus neuronal firing, leading to a suppression of norepinephrine release [
19]. Reduced norepinephrine release from the locus coeruleus to target areas of the body, such as the frontal cortex and amygdala, confines anxiety behavior. Research from human and animal studies has concluded that chronic treadmill and running-wheel exercise increase the expression of the galanin gene in the locus coeruleus [
19]. There has also been a conclusion that the levels of plasma galanin are increased in humans after acute exercise. Norepinephrine plays a role in both the physical and psychological side. Norepinephrine participates in commanding the consolidation and retrieval of emotional memory [
19]. Research has concluded that both chronic treadmill and wheel exercise increase the levels of norepinephrine in the pons and medulla area, as well as the spinal cord as compared to sedentary controls [
19]. In relation to these findings, brain regions linked to cognitive function are elevated by chronic treadmill exercise. These brain regions include the hippocampus and the central and medial amygdala. Additionally, exercise increases the endogenous activity of norepinephrine in which research suggests a linkage between norepinephrine and exercise-enhanced cognitive function [
19]. Norepinephrine plays a major role in an athlete's primary functions due to its various involvements in both exercise related activity as well as cognitive functioning. Norepinephrine has a positive correlation with exercise which is important as an athlete’s lifestyle revolves around exercise. Although norepinephrine is promising in the activities of exercise and cognitive functions, elevated levels can expose athletes to different consequences such as anxiety. Since norepinephrine is a stress hormone present in the fight or flight response, it can have undesirable effects when stress is maintained for a long period of time. Norepinephrine’s primary goal is to direct resources away from maintenance, regeneration, and towards any system required for active movement [
21]. Therefore, prolonged exposure to stress with overproduction of norepinephrine can reduce the resources sent to vital organ systems. In addition, norepinephrine has the ability to increase anxiety since it is a hormone involved in the fight or flight response. An overproduction during stressful situations that athletes can be exposed to due to the pressure put on them can increase their susceptibility to anxiety and anxious tendencies. The locus coeruleus, where norepinephrine’s noradrenergic neurons are located, is the region of the brain that produces the panic response [
21]. There was an animal research study done with mice and rats that discovered when the neurons that contain norepinephrine fire inside of the locus coeruleus, anxious behavior was observed [
21]. Therefore, there has been a conclusion that this mechanism can further exaggerate in individuals diagnosed with anxiety disorders. If an athlete already struggles in day to day life with anxiety, and has developed coping mechanisms to keep it at ease, an overproduction of norepinephrine can be harmful and increase the anxiety causing the individual to believe they have lost control. This can be detrimental to their performance as the athlete becomes more susceptible to struggling with their mental health which then can decrease their performance. This can cause these athletes to spiral into an identity crisis as they begin to not be able to perform at their sport and unable to control their anxiety. Therefore, it is important to recognize how impactful stressful and high pressure environments are on the body. The constant exposure without proper rest and coping mechanisms can cause changes in the body that the athletes are unaware of and believe that they are out of control.
Hormones are incredibly important in the regulation of bodily functions. However, what is not commonly recognized is that environmental factors, even social environmental factors, can directly affect psychological functioning. This lack of knowledge around this can be detrimental, especially in the world of athletics. High stress levels and stressful situations can almost immediately change hormone levels, therefore automatically affecting performance. In the athletic world, usually only the physical is analyzed in order to increase training. It is commonly assumed that training hard and developing the body into the best physical shape will guarantee high performance levels. Although physical training is extremely important in athletics, mental “training” and psychological regulation are just as important in sports performance.