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Chemical Characterization and Evaluation of the Antimicrobial Activity of Extracts from Two Cultivars of Cannabis sativa L. (Tisza and Kompolti) Grown in Sardinia
Juliano, C.C.A.; Mattu, I.; Marchetti, M.; Usai, M. Chemical Characterization and Evaluation of the Antimicrobial Activity of Extracts from Two Cultivars of Cannabis sativa L. (Tisza and Kompolti) Grown in Sardinia. Appl. Sci.2024, 14, 3353.
Juliano, C.C.A.; Mattu, I.; Marchetti, M.; Usai, M. Chemical Characterization and Evaluation of the Antimicrobial Activity of Extracts from Two Cultivars of Cannabis sativa L. (Tisza and Kompolti) Grown in Sardinia. Appl. Sci. 2024, 14, 3353.
Juliano, C.C.A.; Mattu, I.; Marchetti, M.; Usai, M. Chemical Characterization and Evaluation of the Antimicrobial Activity of Extracts from Two Cultivars of Cannabis sativa L. (Tisza and Kompolti) Grown in Sardinia. Appl. Sci.2024, 14, 3353.
Juliano, C.C.A.; Mattu, I.; Marchetti, M.; Usai, M. Chemical Characterization and Evaluation of the Antimicrobial Activity of Extracts from Two Cultivars of Cannabis sativa L. (Tisza and Kompolti) Grown in Sardinia. Appl. Sci. 2024, 14, 3353.
Abstract
The present work was aimed at the chemical characterization and antimicrobial activity of some extracts of aerial parts (essential oils from leaves and inflorescences, and resins from inflorescences) of two legal hemp (Cannabis sativa) varieties, Tisza and Kompolti, grown in Sardinia. Chemical characterization was carried out by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS) techniques. The antimicrobial activity of these extracts against a panel of microorganisms was also determined via minimum inhibitory concentration (M.I.C.) determination. While the results showed a minor or negligible antimicrobial activity of the extracts against Gram+ and Candida strains, a good antibacterial activity (especially of resins) was recorded against S. aureus; no substantial differences were detected between of the chemical compositions of the two Cannabis varieties.
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