Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Gene-Edited Medicinal ‘Superplants’: Advancements for Prolonged Space Travel

Version 1 : Received: 27 February 2024 / Approved: 28 February 2024 / Online: 28 February 2024 (14:01:24 CET)

How to cite: Nair, S. Gene-Edited Medicinal ‘Superplants’: Advancements for Prolonged Space Travel. Preprints 2024, 2024021643. https://doi.org/10.20944/preprints202402.1643.v1 Nair, S. Gene-Edited Medicinal ‘Superplants’: Advancements for Prolonged Space Travel. Preprints 2024, 2024021643. https://doi.org/10.20944/preprints202402.1643.v1

Abstract

Space exploration is an arduous journey, with future explorations extending in duration, increasing the risk for common space-related health issues such as bone density loss due to microgravity, impaired gut microbiota, cardiovascular ailments, and exposure to cosmic radiation. These ailments can be addressed using medicinal plants. Enhancing their efficacy entails employing gene editing to target specific secondary metabolite pathways associated with therapeutic properties. Moreover, gene editing can combine multiple medicinal properties from various plants, culminating in a singular 'superplant' with enhanced therapeutic benefits. This review discusses the current usage of medicinal plants in promoting human health during space travel, the application of gene editing technology in modifying medicinal plants and presents a vision for the utilization of gene-edited medicinal plants in space to mitigate the risk of various space-related health issues.

Keywords

Medicinal plants, long-duration space flight, gene-editing, radiation-induced cardiovascular disease, gut microbiome, microgravity 

Subject

Environmental and Earth Sciences, Other

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