Version 1
: Received: 3 February 2024 / Approved: 5 February 2024 / Online: 5 February 2024 (16:29:39 CET)
How to cite:
Shah, S.; Ikram, J.; Khan, M.W.Z. Molecular Process Of Trigeminal Neuralgia, its Pharmacologic, and Comparison of Surgical Treatment Options with Outcomes. Preprints2024, 2024020303. https://doi.org/10.20944/preprints202402.0303.v1
Shah, S.; Ikram, J.; Khan, M.W.Z. Molecular Process Of Trigeminal Neuralgia, its Pharmacologic, and Comparison of Surgical Treatment Options with Outcomes. Preprints 2024, 2024020303. https://doi.org/10.20944/preprints202402.0303.v1
Shah, S.; Ikram, J.; Khan, M.W.Z. Molecular Process Of Trigeminal Neuralgia, its Pharmacologic, and Comparison of Surgical Treatment Options with Outcomes. Preprints2024, 2024020303. https://doi.org/10.20944/preprints202402.0303.v1
APA Style
Shah, S., Ikram, J., & Khan, M.W.Z. (2024). Molecular Process Of Trigeminal Neuralgia, its Pharmacologic, and Comparison of Surgical Treatment Options with Outcomes. Preprints. https://doi.org/10.20944/preprints202402.0303.v1
Chicago/Turabian Style
Shah, S., Jibran Ikram and Malik Waleed Zeb Khan. 2024 "Molecular Process Of Trigeminal Neuralgia, its Pharmacologic, and Comparison of Surgical Treatment Options with Outcomes" Preprints. https://doi.org/10.20944/preprints202402.0303.v1
Abstract
According to published descriptions, one of the most incapacitating forms of orofacial pain is trigeminal neuralgia (TN). At its core, trigeminal neuropathic pain (TN) is still a clinical diagnostic that has to be differentiated from other forms of TN and face pain linked to other neuralgias or headache disorders. Imaging can only help with the cause of the pain, whether it’s a vascular origin or not. It is becoming more and more evident that there is no one-size-fits-all medication or surgical procedure that can effectively treat every patient with trigeminal neuralgia (TN). This is probably because TN is a diverse collection of conditions that all present with face discomfort. Medical therapy using anticonvulsants like carbamazepine is still the first-line treatment for TN. If this doesn't work for the patient, surgical treatments are available. Microvascular decompression is often a safe, efficient operation with results that are both rapid and long-lasting. Patients who may benefit from percutaneous techniques such as radiofrequency ablation, glycerol ablation, balloon compression, or a combination, include those who cannot undergo general anesthesia or whose medical conditions prohibit a suboccipital craniectomy. Radiosurgery may be a great option for patients with bleeding diathesis brought on by blood-thinning medications who are not eligible for invasive procedures or who do not want to undergo open surgical procedures, as long as the patient is aware that achieving maximum pain relief may take several months. In conclusion, peripheral neurectomies persist in offering a low-cost and resource-saving substitute for pain management to those residing in areas with restricted financial and healthcare resources. In the end, developing a better understanding of the molecular processes behind trigeminal neuralgia will lead to new, less intrusive, and more effective treatments.
Keywords
Trigeminal Neuralgia; Treatment of TN; Neurosurgery; Radiosurgery; Facial pain
Subject
Medicine and Pharmacology, Neuroscience and Neurology
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
