Preprint Concept Paper Version 1 Preserved in Portico This version is not peer-reviewed

A Novel Mathematical Approach with a Correlating Computational Framework for Precisifying Aneurysmal Therapeutics

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Version 1 : Received: 20 January 2024 / Approved: 22 January 2024 / Online: 22 January 2024 (07:48:14 CET)

How to cite: Deouskar, A.; Agrawal, D. A Novel Mathematical Approach with a Correlating Computational Framework for Precisifying Aneurysmal Therapeutics. Preprints 2024, 2024011564. https://doi.org/10.20944/preprints202401.1564.v1 Deouskar, A.; Agrawal, D. A Novel Mathematical Approach with a Correlating Computational Framework for Precisifying Aneurysmal Therapeutics. Preprints 2024, 2024011564. https://doi.org/10.20944/preprints202401.1564.v1

Abstract

Abdominal aortic aneurysm (AAA) is a chronic disease in which the abdominal aorta expands until it ruptures. AAA incidence: 10 million/year (India), deaths: 40%-90% (13th leading cause of death in the USA). Current treatment methods make diagnosis difficult due to the lack of noticeable symptoms and inaccurately planned operations. Rupture Scope is a mathematical model to dramatically reduce AAA deaths and improve treatment efficiency. Using a case-specific replica/simulation of real-time abdominal aortic blood flow for monitoring without frequent imaging scans and a novel derived mathematical linear regression model to predict rupture date and expansion rate with an overall accuracy of 95.64%.

Keywords

Abdominal aortic aneurysm; Mathematical Linear Regression; Computational Fluid Dynamics; Dynamical Systems

Subject

Computer Science and Mathematics, Mathematical and Computational Biology

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