Version 1
: Received: 14 January 2024 / Approved: 15 January 2024 / Online: 16 January 2024 (09:41:54 CET)
How to cite:
Popovici, G.; Georgescu, C.; Vasile, C.; Mihailov, O.; Vasile, M.; Arbune, M. The Impact of COVID-19 on the Tuberculosis Outcomes in a Pneumology Hospital from South-East Romania. Preprints2024, 2024011145. https://doi.org/10.20944/preprints202401.1145.v1
Popovici, G.; Georgescu, C.; Vasile, C.; Mihailov, O.; Vasile, M.; Arbune, M. The Impact of COVID-19 on the Tuberculosis Outcomes in a Pneumology Hospital from South-East Romania. Preprints 2024, 2024011145. https://doi.org/10.20944/preprints202401.1145.v1
Popovici, G.; Georgescu, C.; Vasile, C.; Mihailov, O.; Vasile, M.; Arbune, M. The Impact of COVID-19 on the Tuberculosis Outcomes in a Pneumology Hospital from South-East Romania. Preprints2024, 2024011145. https://doi.org/10.20944/preprints202401.1145.v1
APA Style
Popovici, G., Georgescu, C., Vasile, C., Mihailov, O., Vasile, M., & Arbune, M. (2024). The Impact of COVID-19 on the Tuberculosis Outcomes in a Pneumology Hospital from South-East Romania. Preprints. https://doi.org/10.20944/preprints202401.1145.v1
Chicago/Turabian Style
Popovici, G., Mihaela-Camelia Vasile and Manuela Arbune. 2024 "The Impact of COVID-19 on the Tuberculosis Outcomes in a Pneumology Hospital from South-East Romania" Preprints. https://doi.org/10.20944/preprints202401.1145.v1
Abstract
The COVID-19 pandemic and tuberculosis have epidemiological similarities, being transmitted airborne, favored by direct contact, crowded environments and vulnerable biological status. We performed a retrospective study of 45 cases of pulmonary tuberculosis associated with COVID-19 (TB+COV+) compared to 45 cases with tuberculous monoinfection (TB+COV-), hospitalized during 2021-2022. The demographic characteristics were similar in the two groups, predominating men, a median age of 51 years, living in rural areas, medium level of education and smoking. Common symptoms of the two groups were cough, weight loss, profuse sweating, loss of appetite and hemoptysis, while fever, headache, myo-arthralgias and digestive symptoms characterized the TB+COV+ forms. The scores of radiological lesions in the TB+COV+ compared to TB+COV- group were significantly higher and persistent, revealing more frequent bilateral extensive lung lesions. There were no significant differences in the biological parameters between the two groups. Mortality was 2.2%, regardless of the association of COVID-19. The frequency of infections with Clostridioides difficile was higher in TB+COV+ cases. In conclusion, the co-infection of COVID-19 had an impact on the clinical and biological expression of tuberculosis diagnosed in a pandemic context.
Keywords
tuberculosis; COVID-19 pandemic; co-infection; Romania
Subject
Medicine and Pharmacology, Pulmonary and Respiratory Medicine
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
