Preprint Article Version 1 Preserved in Portico This version is not peer-reviewed

Pregnancy Outcomes, Miscarriage and Live Birth Rates Following the Transfer of Thawed Vitrified Embryos Derived from IVF vs. ICSI, A Retrospective Analysis

Avi Zolotarevsky
* ORCID logo ,
Ido Feferkorn
ORCID logo ,
Nadav Cohen
,
Chen Nahshon
ORCID logo ,
Idit Blais
,
Shirley Lahav-Baratz
,
Mara Koifman
,
Martha Dirnfeld
Version 1 : Received: 3 January 2024 / Approved: 4 January 2024 / Online: 4 January 2024 (15:33:35 CET)

How to cite: Zolotarevsky, A.; Feferkorn, I.; Cohen, N.; Nahshon, C.; Blais, I.; Lahav-Baratz, S.; Koifman, M.; Dirnfeld, M. Pregnancy Outcomes, Miscarriage and Live Birth Rates Following the Transfer of Thawed Vitrified Embryos Derived from IVF vs. ICSI, A Retrospective Analysis. Preprints 2024, 2024010388. https://doi.org/10.20944/preprints202401.0388.v1 Zolotarevsky, A.; Feferkorn, I.; Cohen, N.; Nahshon, C.; Blais, I.; Lahav-Baratz, S.; Koifman, M.; Dirnfeld, M. Pregnancy Outcomes, Miscarriage and Live Birth Rates Following the Transfer of Thawed Vitrified Embryos Derived from IVF vs. ICSI, A Retrospective Analysis. Preprints 2024, 2024010388. https://doi.org/10.20944/preprints202401.0388.v1

Abstract

The present study was conducted to compare embryo survival rate and treatment outcomes including pregnan-cy, miscarriage and live birth rates of IVF and ICSI vitrified-thawed embryo transfers. Authors suggested to compare treatment outcomes [clinical pregnancy, miscarriage, ectopic pregnancy, and live birth rates] after transfer of IVF versus ICSI vitrified-thawed embryos. Cohort retrospective study in the IVF unit at a university af-filiated Medical Center which included 845 frozen thawed embryo transfer cycles of vitrified embryos from treatment cycles between the years 2013-2019. Out of 845 FET cycles of vitrified thawed embryos, 223 clinical pregnancies were achieved [26.4%]. Of these 64 [28.4%] following IVF, 131 [25.6%] after ICSI and 28 [25.9%] in the sibling oocytes group [P =0.631]. Live birth rate did not differ between the three groups: 23.6%, 22.3% and 21.5% for groups IVF, ICSI and IVF+ICSI, respectively [p=0.899]. Sub analysis by age below 35 and above 35 years old revealed no statistical difference between IVF and ICSI cycles in terms of clinical pregnancy, miscarriage, ectopic pregnancy, and live birth rates between the groups. The present study suggests that the technique of insemina-tion has no adverse effect related to vitrification.

Keywords

pregnancy; ICSI; IVF; embryo cryopreservation; vitrification

Subject

Medicine and Pharmacology, Reproductive Medicine

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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