Version 1
: Received: 2 January 2024 / Approved: 3 January 2024 / Online: 3 January 2024 (10:04:52 CET)
How to cite:
Zhao, J.; Sun, J.; Zhang, K.; Wang, S.; Ding, W.; Li, Z. Effect of Positively Charged Lipids (DOTAP) on the Insertion of CNT into Liposomes and Separation Performance of Tfn Membranes. Preprints2024, 2024010120. https://doi.org/10.20944/preprints202401.0120.v1
Zhao, J.; Sun, J.; Zhang, K.; Wang, S.; Ding, W.; Li, Z. Effect of Positively Charged Lipids (DOTAP) on the Insertion of CNT into Liposomes and Separation Performance of Tfn Membranes. Preprints 2024, 2024010120. https://doi.org/10.20944/preprints202401.0120.v1
Zhao, J.; Sun, J.; Zhang, K.; Wang, S.; Ding, W.; Li, Z. Effect of Positively Charged Lipids (DOTAP) on the Insertion of CNT into Liposomes and Separation Performance of Tfn Membranes. Preprints2024, 2024010120. https://doi.org/10.20944/preprints202401.0120.v1
APA Style
Zhao, J., Sun, J., Zhang, K., Wang, S., Ding, W., & Li, Z. (2024). Effect of Positively Charged Lipids (DOTAP) on the Insertion of CNT into Liposomes and Separation Performance of Tfn Membranes. Preprints. https://doi.org/10.20944/preprints202401.0120.v1
Chicago/Turabian Style
Zhao, J., Wande Ding and Zhengping Li. 2024 "Effect of Positively Charged Lipids (DOTAP) on the Insertion of CNT into Liposomes and Separation Performance of Tfn Membranes" Preprints. https://doi.org/10.20944/preprints202401.0120.v1
Abstract
Liposome vesicle is an ideal carrier for carbon nanotube (CNT) to serve as the water channel that allows the fast transport of water molecules, and thus enhancing the membrane permeability. However, low quantity of the inserted CNT in the liposome vesicle is an important factor that limited further improvement of the membrane flux. In present study, positively charged lipids (2,3-dioleoyloxy-propyl)-trimethylammonium-chloride (DOTAP) was introduced to the 1,2-dioleoyl-sn-glycero-3-phosphoethanolamineon (DOPE) liposome vesicles to tailor the vesicle charge, so as to evaluate the effect of positively charged DOTAP on the insertion of CNT into liposomes and separation performance of thin-film nanocomposite (TFN) membranes. The results showed that addition of DOTAP induced more quantity of CNT inserted into the liposome vesicles, since the shrinkage rate (k) and permeability (Pf) of liposome vesicles present obvious increase with increased content of DOTAP in the liposome vesicles. Besides, it contributed to 252.3% higher water flux for TFN membranes containing DOPE/DOTAP2:1-CNT liposomes (the mass ratio between DOPE and DOTAP was 2:1) than TFC membranes. More important, it presented 106.7% higher water flux for TFN membranes containing DOPE/DOTAP4:1-CNT liposomes (the mass ratio between DOPE and DOTAP was 4:1), which was originated from the more water channels that the CNT provided in the liposome vesicles. In all, positively charged DOTAP effectively tailored the vesicle charge, which provided a better carrier for the insertion of more quantity of CNT, and contributed to higher permeability of TFN membranes.
Copyright:
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
