Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

Multidisciplinary and Tailored Treatment of LABC in Progression during NAC: Case Report

Letizia Cuniolo
* ,
Marco Gipponi
* ,
Federica Murelli
,
Francesca Depaoli
,
Chiara Cornacchia
,
Simonetta Franchelli
,
Marianna Pesce
,
Elena Ronda
,
Stefano Picardi
,
Raquel Diaz
,
Daniele Friedman
,
Franco De Cian
,
Piero Fregatti
Version 1 : Received: 19 December 2023 / Approved: 20 December 2023 / Online: 20 December 2023 (09:34:39 CET)

How to cite: Cuniolo, L.; Gipponi, M.; Murelli, F.; Depaoli, F.; Cornacchia, C.; Franchelli, S.; Pesce, M.; Ronda, E.; Picardi, S.; Diaz, R.; Friedman, D.; De Cian, F.; Fregatti, P. Multidisciplinary and Tailored Treatment of LABC in Progression during NAC: Case Report. Preprints 2023, 2023121485. https://doi.org/10.20944/preprints202312.1485.v1 Cuniolo, L.; Gipponi, M.; Murelli, F.; Depaoli, F.; Cornacchia, C.; Franchelli, S.; Pesce, M.; Ronda, E.; Picardi, S.; Diaz, R.; Friedman, D.; De Cian, F.; Fregatti, P. Multidisciplinary and Tailored Treatment of LABC in Progression during NAC: Case Report. Preprints 2023, 2023121485. https://doi.org/10.20944/preprints202312.1485.v1

Abstract

Locally Advanced Breast Cancer (LABC) is a complex disease that requires a multidisciplinary approach. Neoadjuvant Chemotherapy (NAC) is usually performed in order to achieve loco-regional radical resection; although its importance in the multidisciplinary approach to LABC is well recognised, a small number of patients show Progressive Disease (PD). No standard Salvage Treatment (ST) has been defined and different strategies can be adopted, such as second line systemic therapies, radiation therapy, and surgery. Herein a case of LABC in PD during NAC is reported with a literature review, with the aim of highlighting the importance of a tailored multidisciplinary treatment in each patient.

Keywords

Locally Advanced Breast Cancer (LABC); Progressive Disease (PD); Salvage Treatment (ST)

Subject

Medicine and Pharmacology, Surgery

Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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