Preprint Review Version 1 Preserved in Portico This version is not peer-reviewed

Pharmacotherapy of Dyslipidemias

Version 1 : Received: 15 December 2023 / Approved: 15 December 2023 / Online: 15 December 2023 (19:00:11 CET)

A peer-reviewed article of this Preprint also exists.

de Oliveira, L.L.H.; de Assis, A.C.R.; Giraldez, V.Z.R.; Scudeler, T.L.; Soares, P.R. Dyslipidemia: A Narrative Review on Pharmacotherapy. Pharmaceuticals 2024, 17, 289. de Oliveira, L.L.H.; de Assis, A.C.R.; Giraldez, V.Z.R.; Scudeler, T.L.; Soares, P.R. Dyslipidemia: A Narrative Review on Pharmacotherapy. Pharmaceuticals 2024, 17, 289.

Abstract

Hypercholesterolemia plays a fundamental role in the development and progression of atherosclerosis. Current guidelines for treating dyslipidemia target low-density lipoprotein-cholesterol (LDL-C). Despite advances in the pharmacotherapy of atherosclerosis, the most successful agents used to treat this disease – statins – remain insufficient in the primary or secondary prevention of acute myocardial infarction. Advancing therapy for hypercholesterolemia with emerging new drugs, either as monotherapy or in combination, is expected to improve cardiovascular outcomes.

Keywords

dyslipidemias; cholesterol; statins; gene therapy

Subject

Medicine and Pharmacology, Cardiac and Cardiovascular Systems

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