Preprint Case Report Version 1 Preserved in Portico This version is not peer-reviewed

A Case of Severe Acute Renal Failure Due to Oxalate Crystal Deposition Induced Severe Interstitial Nephritis: A Case Report and Literature Review.

Version 1 : Received: 5 December 2023 / Approved: 6 December 2023 / Online: 6 December 2023 (10:15:11 CET)

How to cite: Errabelli, P.; Lathiya, M.; Roy, S.; Mareedu, N. A Case of Severe Acute Renal Failure Due to Oxalate Crystal Deposition Induced Severe Interstitial Nephritis: A Case Report and Literature Review.. Preprints 2023, 2023120325. https://doi.org/10.20944/preprints202312.0325.v1 Errabelli, P.; Lathiya, M.; Roy, S.; Mareedu, N. A Case of Severe Acute Renal Failure Due to Oxalate Crystal Deposition Induced Severe Interstitial Nephritis: A Case Report and Literature Review.. Preprints 2023, 2023120325. https://doi.org/10.20944/preprints202312.0325.v1

Abstract

This case report describes a 71-year-old female with multiple comorbidities who presented with symptoms suggestive of stroke and was subsequently found to have severe acute kidney injury (AKI) due to acute interstitial nephritis (AIN). The patient has normal kidney function at baseline. She has been on hydrochlorothiazide and metoprolol succinate for hypertension for several years. Due to severe acute kidney injury, a kidney biopsy was performed, revealing severe Acute Interstitial Nephritis secondary and multiple intratubular oxalate crystals. The patient's renal function improved after withdrawing HCTZ, volume repletion and initiating prolonged prednisone taper. We attempt to provide some insights through our paper into the mechanism of acute renal failure from crystal nephropathy and its management.

Keywords

oxalate crystal nephrpathy; acute renal failure

Subject

Medicine and Pharmacology, Clinical Medicine

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