Xu, Z.; Li, Z.; Liu, C.; Yang, K.; Ge, H. Palladium-Catalyzed β-C(sp3)–H Bond Arylation of Tertiary Aldehydes Facilitated by 2-Pyridone Ligands. Molecules2024, 29, 259.
Xu, Z.; Li, Z.; Liu, C.; Yang, K.; Ge, H. Palladium-Catalyzed β-C(sp3)–H Bond Arylation of Tertiary Aldehydes Facilitated by 2-Pyridone Ligands. Molecules 2024, 29, 259.
Xu, Z.; Li, Z.; Liu, C.; Yang, K.; Ge, H. Palladium-Catalyzed β-C(sp3)–H Bond Arylation of Tertiary Aldehydes Facilitated by 2-Pyridone Ligands. Molecules2024, 29, 259.
Xu, Z.; Li, Z.; Liu, C.; Yang, K.; Ge, H. Palladium-Catalyzed β-C(sp3)–H Bond Arylation of Tertiary Aldehydes Facilitated by 2-Pyridone Ligands. Molecules 2024, 29, 259.
Abstract
2-Pyridone ligand-facilitated palladium-catalyzed direct C–H bond functionalization via the transient directing group strategy has become an attractive topic. Here we report a Pd-catalyzed direct β-C(sp3) –H arylation reaction of tertiary aliphatic aldehydes by using an α-amino acid as a transient directing group in combination with a 2-pyridone ligand.
Chemistry and Materials Science, Organic Chemistry
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