Short Note
Version 1
Preserved in Portico This version is not peer-reviewed
1-(2,5-Dimethoxy-4-nitrophenyl)piperidine and 1-(2,5-dimethoxy-4-nitrophenyl)pyrroridine
Version 1
: Received: 14 November 2023 / Approved: 14 November 2023 / Online: 15 November 2023 (09:06:32 CET)
A peer-reviewed article of this Preprint also exists.
Syeda, T.M.; Al-Shaidi, M.R.; Basri, I.; Merzouk, M.; Aldabbagh, F. 1-(2,5-Dimethoxy-4-nitrophenyl)piperidine. Molbank 2023, 2023, M1744. Syeda, T.M.; Al-Shaidi, M.R.; Basri, I.; Merzouk, M.; Aldabbagh, F. 1-(2,5-Dimethoxy-4-nitrophenyl)piperidine. Molbank 2023, 2023, M1744.
Abstract
Treatment of the non-purified mixture of dinitro isomers obtained from the nitration of 1,4-dimethoxybenzene with piperidine, led to the isolation of novel but minor adduct, 1-(2,5-dimethoxy-4-nitrophenyl)piperidine (2b) in 15% yield. Yields of nucleophilic aromatic substitution adducts are high when using purified 1,4-dimethoxy-2,5-dinitrobenzene (1b) with piperidine and pyrrolidine to give 2b and 1-(2,5-dimethoxy-4-nitrophenyl)pyrrolidine (3b) in 76% and 82%, respectively.
Keywords
benzimidazolequinone, nitration; nitrobenzene; nucleophilic aromatic substitution
Subject
Chemistry and Materials Science, Organic Chemistry
Copyright: This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Comments (0)
We encourage comments and feedback from a broad range of readers. See criteria for comments and our Diversity statement.
Leave a public commentSend a private comment to the author(s)
* All users must log in before leaving a comment
